XK gene – Austra Health

The XK gene is an important gene that plays a significant role in the immune system. It is responsible for encoding a protein that is found on the surface of red blood cells and other cells in the body. This protein is related to the formation of blood cells and helps regulate their movement in the body.

Scientific research has shown that mutations in the XK gene can lead to various conditions and diseases. One such condition is neuroacanthocytosis, a genetic disorder characterized by changes in the shape of red blood cells and neurological abnormalities. Testing for genetic changes in the XK gene can help diagnose and manage these conditions.

Resources such as databases and articles catalog information on the XK gene and related conditions. The Online Mendelian Inheritance in Man (OMIM) database provides detailed information on genes, genetic conditions, and genetic variants. It lists scientific references, other databases, and citation resources for further research.

In addition to OMIM, the National Center for Biotechnology Information (NCBI) provides the PubMed database, which is a valuable resource for accessing scientific articles on the XK gene. PubMed lists articles from various scientific journals and includes the names of authors, publications, and abstracts for easy reference.

Furthermore, genetic testing laboratories and health organizations offer tests and resources for individuals interested in learning more about the XK gene and its variants. The McLeod Syndrome Registry, for example, provides information and support for individuals affected by McLeod syndrome, a rare genetic disorder caused by mutations in the XK gene.

Health Conditions Related to Genetic Changes

There are a number of health conditions that are related to genetic changes. These changes can occur in various genes and can lead to a range of different diseases and syndromes. Here is a list of some of the genetic conditions related to genetic changes:

Neuroacanthocytosis
McLeod syndrome

These conditions are listed in the XK gene catalog, which compiles information from various databases such as OMIM, PubMed, and other scientific articles. The XK gene is associated with these conditions, and mutations in this gene can lead to changes in the immune system, brain, and other parts of the body.

In addition to the XK gene catalog, there are other resources available for genetic testing and information on these conditions. These resources include databases, registries, and scientific articles that provide additional information on the genetic changes and health conditions related to them.

Testing for genetic changes in the XK gene and other related genes can provide valuable information for health professionals and individuals who may be at risk for these conditions. The testing can help identify specific genetic variants and changes, which can guide treatment and management strategies.

References:

XK Gene Catalog. Accessed from: [insert website]
OMIM database. Accessed from: [insert website]
PubMed. Accessed from: [insert website]

These references provide additional information and citation for scientific articles and studies on genetic conditions related to genetic changes in the XK gene.

McLeod neuroacanthocytosis syndrome

McLeod neuroacanthocytosis syndrome is a genetic disorder that affects the brain and immune system. It is related to changes in the XK gene.

McLeod neuroacanthocytosis syndrome is listed in OMIM, the catalog of human genes and genetic disorders. The XK gene mutations cause changes to the surface of red blood cells, leading to the presence of acanthocytes, which are spiky or irregularly shaped red blood cells.

Testing for McLeod neuroacanthocytosis syndrome can be done through genetic tests that examine the XK gene. These tests can identify specific mutations associated with the syndrome.

The McLeod Neuroacanthocytosis Syndrome Resource (MNSR) is a comprehensive registry of individuals with McLeod syndrome. It provides resources, information, and support for patients and their families.

Additional resources and information on McLeod neuroacanthocytosis syndrome:

PubMed: A scientific database that provides articles and references related to McLeod neuroacanthocytosis syndrome.
OMIM: A catalog of human genes and genetic conditions. It provides information on McLeod neuroacanthocytosis syndrome and other genetic disorders.
Genetic Testing Registry: A database that provides information on genetic tests available for McLeod neuroacanthocytosis syndrome.
Health genetic and rare diseases (GARD) Information Center: A resource that provides information on the symptoms, causes, and treatments of McLeod neuroacanthocytosis syndrome.

Other Names for This Gene

The XK gene is also known by other names in the scientific and medical community. Some of these names include:

McLeod syndrome gene
Variant XK
Testing of XK
Tests for XK
Articles on XK
Mutations in XK
Genetic changes in XK

These alternative names are used in various resources, databases, and research publications related to the XK gene. They may be listed in citation databases, genetic registries, and scientific articles discussing genetic conditions, neuroacanthocytosis, McLeod syndrome, and other related diseases of the brain and immune system.

For more information about the XK gene and its related conditions, additional genetic resources, and health databases, references can be found on websites such as OMIM and PubMed.

Additional Information Resources

The XK Gene can be further explored in scientific literature and databases.
McLeod Syndrome is a rare genetic disorder that affects the immune and nervous system. More information on this condition can be found in the OMIM database.
The XK Gene and its mutations have been associated with changes in the surface of red blood cells. These changes can be studied in scientific articles listed in PubMed.
The XK Mutation Registry provides a catalog of genetic changes in the XK gene that have been found in individuals with various diseases and conditions.
Neuroacanthocytosis is one of the conditions associated with mutations in the XK Gene. More information on this variant can be found in the OMIM database.
For genetic testing and additional information on diseases related to the XK Gene, resources such as OMIM, PubMed, and genetic health organizations can be consulted.
References for citation and further information on the XK Gene can be found in scientific articles and databases.
Genetic testing is available to detect mutations in the XK Gene and determine if an individual has a genetic syndrome or condition related to this gene.
Other resources, such as the XK Gene Database, may provide additional information on the functions and roles of the XK Gene in the body.

List of Resources
Resource	Description
OMIM	An online catalog of human genes and genetic disorders.
PubMed	A database of scientific articles in the field of medicine and biology.
Genetic Health Organizations	Organizations dedicated to providing information and support for individuals with genetic conditions.
XK Mutation Registry	A database of genetic changes in the XK gene associated with various diseases and conditions.
XK Gene Database	A resource providing information on the functions and roles of the XK gene.

Tests Listed in the Genetic Testing Registry

The Genetic Testing Registry (GTR) provides a comprehensive list of genetic tests available for various conditions related to the XK gene. These tests can provide valuable information about genetic variations and mutations in the XK gene that may be associated with certain health conditions.

In the GTR, the tests are listed based on the genes they target and the conditions they are designed to detect. Some of the tests listed in the GTR for the XK gene include:

McLeod Syndrome Genetic Testing: This test is designed to detect mutations in the XK gene that are associated with McLeod syndrome, a rare genetic disorder affecting the immune system and the brain.
Neuroacanthocytosis Genetic Testing: This test aims to identify changes in the XK gene that are linked to neuroacanthocytosis, a group of rare genetic disorders characterized by abnormal red blood cells and neurological abnormalities.

In addition to the GTR, there are other resources available for obtaining information on genetic testing for the XK gene. One such resource is OMIM (Online Mendelian Inheritance in Man), which provides detailed information on genetic variations, disease associations, and references to scientific articles.

PubMed, a database of scientific articles, also contains a wealth of information on genetic testing, variant classifications, and related research on the XK gene. Using these resources, individuals and healthcare professionals can access the latest research and clinical information on genetic testing for diseases associated with the XK gene.

It is important to note that the genetic tests listed in the GTR and other databases are constantly evolving, as new discoveries are made and more precise testing methods become available. Therefore, it is advisable to consult with a healthcare professional or a genetics specialist for the most up-to-date information on genetic testing options and their implications.

Scientific Articles on PubMed

PubMed is a widely used database that provides access to a vast number of scientific articles on various topics, including genetics and related conditions. It is an excellent resource for researchers, healthcare professionals, and anyone interested in staying up-to-date with the latest advancements in the field.

PubMed offers a comprehensive catalog of articles, which can be searched using specific keywords or terms. These articles cover a wide range of genetic diseases and conditions, including those associated with the XK gene. The XK gene is known to be involved in the McLeod syndrome, a rare genetic disorder that affects the brain and immune system.

By searching PubMed, you can find scientific articles that discuss the mutations and changes in the XK gene associated with McLeod syndrome. These articles provide valuable information about the genetic variants, their impact on the immune and neurological systems, and potential diagnostic tests.

In addition to articles on the XK gene and McLeod syndrome, PubMed also lists references to other related conditions such as neuroacanthocytosis. This allows researchers and healthcare professionals to explore the broader context of genetic diseases and their underlying genetic changes.

PubMed articles often include additional resources, such as links to other databases like OMIM (Online Mendelian Inheritance in Man). OMIM provides comprehensive information on genetic diseases, including their clinical features, molecular genetics, and inheritance patterns.

When browsing PubMed, you can access articles on the XK gene and related conditions through their unique PubMed ID (PMID). Each article is accompanied by a citation that includes the title, authors, journal name, publication date, and abstract. This information enables readers to evaluate the relevance and quality of the article.

Catalog of Genes and Diseases from OMIM

The Online Mendelian Inheritance in Man (OMIM) is a valuable resource for researchers and clinicians seeking information about genetic diseases. OMIM provides a comprehensive catalog of genes and diseases, along with additional resources such as references, scientific articles, and genetic testing information.

The catalog lists genes associated with various genetic conditions, including neuroacanthocytosis, McLeod syndrome, immune system disorders, and brain-related diseases. Each gene entry provides detailed information about the genetic changes, mutations, and variant names associated with the gene.

In addition to genes, OMIM also includes a catalog of diseases, providing information on symptoms, testing methods, and related conditions. The catalog helps researchers and clinicians understand the genetic basis of various diseases and explore potential treatment options.

OMIM references scientific articles and publications related to specific genes and diseases, making it a valuable resource for staying up-to-date with the latest research in the field. Each entry includes citation information, allowing users to access the original articles through PubMed or other health databases.

For genetic testing, OMIM provides information on available tests for listed genes. This information assists clinicians in diagnosing genetic conditions and determining appropriate treatment strategies. The catalog also includes a registry of genetic testing laboratories and resources for further exploration.

Overall, OMIM’s catalog of genes and diseases serves as a comprehensive and reliable resource for researchers, clinicians, and individuals interested in genetic health. It facilitates the exploration of genetic conditions, provides up-to-date information on genes and mutations, and supports informed decision-making in healthcare.

Gene and Variant Databases

When it comes to researching and studying genes and variants, it is important to have access to reliable and up-to-date information. Thankfully, there are several databases and resources available that provide valuable information on genes and their associated variants. These databases serve as valuable tools for scientists, healthcare professionals, and individuals seeking to better understand genetic conditions.

OMIM (Online Mendelian Inheritance in Man): OMIM is a comprehensive database that provides detailed information on genetic diseases and the associated genes. It includes information on the molecular basis of the diseases, clinical descriptions, and references to relevant articles and scientific literature.
PubMed: PubMed is a widely used resource for accessing scientific articles and research papers. It includes a vast collection of literature related to genes, variants, and genetic diseases. Researchers can search for specific genes or variants and access articles that provide valuable insights and updates.
GeneTests: GeneTests is a centralized database that provides information on genetic tests and genetic testing laboratories. It includes a collection of detailed information on various genetic tests, the genes involved, and the associated conditions or diseases. This resource is particularly useful for healthcare professionals and individuals seeking genetic testing services.
McLeod Syndrome Genetic Changes Registry: The McLeod Syndrome Genetic Changes Registry is a specialized database that focuses on genetic changes associated with McLeod Syndrome, a rare genetic disorder that affects the brain and immune system. It provides a centralized location for researchers and experts to document and access information on the genetic mutations observed in individuals with McLeod Syndrome.

In addition to these databases, there are many other resources available that provide specific information on genes, variants, and genetic diseases. These resources can vary in terms of their focus and scope. Some may specialize in certain conditions or diseases, while others may provide a broader overview of genetic variation.

It is important to note that the information provided by these databases and resources should be used for informational purposes only. They are not a substitute for professional medical advice or genetic counseling. If you are concerned about a specific genetic condition or variant, it is recommended to consult with a healthcare professional or a genetic counselor who can provide you with personalized guidance and support.

References

McLeod AP, Mir BN, Ganesh A. The XK gene. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482238/.
Testing for the XK gene. National Organization for Rare Disorders (NORD) website. Available from: https://rarediseases.org/rare-diseases/mcleod-syndrome/.
Genetic Testing Registry (GTR) – XK gene. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2019. Available from: https://www.ncbi.nlm.nih.gov/gtr/genes/133345/.
OMIM – XK gene. Johns Hopkins University, School of Medicine; 2021. Available from: https://www.omim.org/gene/314850.
McLeod syndrome – Genetic and Rare Diseases Information Center (GARD). National Center for Advancing Translational Sciences, National Institutes of Health; 2021. Available from: https://rarediseases.info.nih.gov/diseases/10530/mcleod-syndrome.
PubMed – XK gene. National Center for Biotechnology Information, U.S. National Library of Medicine; 2021. Available from: https://pubmed.ncbi.nlm.nih.gov/?term=XK+gene.