Vosoritide

Vosoritide is used to increase linear growth (height) in certain children 5 years of age or older who have achondroplasia (ACH; achondroplastic dwarfism; a genetic condition of bone growth that results in short arms and legs). Vosoritide is in a class of medications called C type natriuretic peptide (CNP) analogs. It works by increasing cartilage cell growth which results in increased bone growth.

🔔 How should this medicine be used?

Vosoritide comes as a powder to be mixed with liquid to inject subcutaneously (just under the skin). It is usually injected once a day. Inject vosoritide injection at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use vosoritide injection exactly as directed. Do not use more or less of it or take it more often than prescribed by your doctor.

Vosoritide injection may cause a temporary decrease in blood pressure. Your child should eat a meal and drink 8 to 10 ounces of liquid such as water, milk, or juice within 60 minutes before receiving vosoritide injection. Call your doctor or nurse if your child experiences any of the following symptoms that may occur after the injection: dizziness, tiredness, or nausea.

Your healthcare provider will monitor your child’s growth carefully during treatment with vosoritide injection and will adjust the dose and the length of treatment based on your child’s response to this medication.

If you will be injecting vosoritide injection by yourself at home or having a friend or relative inject the medication for you, your doctor will show you or the person who will be injecting the medication how to mix the medication properly and how to inject it. Before you use vosoritide injection yourself the first time, carefully read the written instructions for use that come with the medication. Ask your doctor or pharmacist if you have any questions about how to mix the medication or do not understand how to inject vosoritide.

Before you are ready to inject vosoritide, you will need to remove the vial of vosoritide and the prefilled diluent syringe from the refrigerator and allow them to warm to room temperature.

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You should always look at vosoritide injection solution (liquid) after mixing and before you inject it. The solution should be clear and colorless to yellow, with no particles in it. Do not use vosoritide injection solution if it is colored, cloudy, contains particles, or if the expiration date on the vial has passed.

Use each syringe only once. Dispose of used syringe in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.

Inject vosoritide into the front of the thighs, buttocks, or anywhere on your stomach except your navel (belly button) and the area 2 inches around it. If another person is injecting your medication, the outer area of the upper arms also may be used. Do not inject the medication into skin that is tender, bruised, damaged, or scarred. Choose a different spot each time you inject the medication.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.