Tebentafusp injection

Tebentafusp injection may cause a serious or life-threatening reaction called cytokine release syndrome (CRS). A doctor or nurse will monitor you carefully during your infusion and for at least 16 hours after your first 3 infusions and then for at least 30 minutes for all the infusions after that. Tell your doctor if you have an inflammatory disorder or if you have or think you may have any type of infection now. If you experience any of the following symptoms during and after your infusion, tell your doctor immediately: fever, chills, fast or irregular heartbeat, muscle pain, shaking, diarrhea, tiredness, weakness, difficulty breathing, shortness of breath, cough, confusion, nausea, vomiting, headache, dizziness, or lightheadedness.

🔔 Why is this medication prescribed?

Tebentafusp injection is used to treat certain types of uveal melanoma (cancer of the eye) that is unable to be surgically removed or has spread to other parts of the body. Tebentafusp is in a class of medications called CD3 T cell receptor engagers. It works by stimulating the immune system to kill cancer cells.

🔔 How should this medicine be used?

Tebentafusp injection comes as a liquid and is injected intravenously (into a vein) by a doctor or nurse in a healthcare setting. It is usually injected slowly over period of 15 to 20 minutes once a week. The length of your treatment depends on how well your body responds to the medication and the side effects that you experience.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

🔔 Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

🔔 What special precautions should I follow?

Before receiving tebentafusp injection,

• tell your doctor and pharmacist if you are allergic to tebentafusp, any other medications, or any of the ingredients in tebentafusp injection. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, or nutritional supplements, you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had liver disease.
• tell your doctor if you are pregnant, or plan to become pregnant. You should not become pregnant while you are taking receiving tebentafusp injection. You will need to have a pregnancy test before you start your treatment with tebentafusp. You should use birth control to prevent pregnancy during your treatment with tebentafusp injection and for 1 week after the final dose. Talk to your doctor about birth control methods that you can use. Tebentafusp may harm your unborn baby. If you become pregnant while receiving tebentafusp injection, call your doctor.
• tell your doctor if you are breastfeeding. You should not breastfeed while you are receiving tebentafusp injection and for at least 1 week after your final dose.

🔔 What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

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