Nafarelin Nasal Spray
Nafarelin nasal spray is used to manage endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes infertility, pain before and during menstrual periods, pain during and after sexual activity, and heavy or irregular bleeding). Nafarelin nasal spray is also used to treat central precocious puberty (CPP; a condition causing children to enter puberty too soon, resulting in faster than normal bone growth and development of sexual characteristics) in young boys and girls. Nafarelin is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by decreasing the amount of certain hormones in the body.
🔔 How should this medicine be used?
Nafarelin comes as a solution (liquid) to spray in the nose. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nafarelin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not stop using nafarelin nasal spray without talking to your doctor.
If you are using nafarelin nasal spray to treat endometriosis, it is usually used twice a day (about 12 hours apart) as one spray in one nostril in the morning and one spray in the other nostril in the evening, for total of 2 sprays per day. Nafarelin should be started between the second and fourth days of your menstrual period. After 2 months and depending on your response, your doctor may increase your dose to 1 spray in each nostril twice a day, for a total of 4 sprays per day. The length of treatment is usually about 6 months.
If you are using nafarelin nasal spray to treat precocious puberty, it is usually sprayed in each nostril 2 or 3 times a day. If you are using nafarelin nasal spray 2 times a day, it is usually used as 2 sprays in each nostril, for a total of 8 sprays per day. It may also be used as 3 sprays in alternating nostrils 3 times a day, for a total of 9 sprays per day.
Avoid sneezing or blowing your nose during or immediately after using nafarelin nasal spray. This decreases nafarelin’s effectiveness.
Before you use nafarelin nasal spray for the first time, read the written directions that come with it. Ask your doctor or pharmacist if you have any questions about how to use the nasal spray.
To use the nasal spray, follow these steps:
- Remove the plastic cap and safety clip from the nasal spray pump.
- If you are using the nasal spray pump for the first time, you must prime the pump. Hold the bottle upright with the applicator between your forefinger and middle finger and your thumb under the bottle. Point the bottle upright and away from your face. Press your thumb and fingers firmly and quickly against the pump 7 to 10 times until you see a fine spray.
- Before and after using nafarelin nasal spray, hold the spray pump horizontally, and rinse the tip of the spray pump with warm water for 15 seconds while wiping the tip with a cloth or your finger. Wipe the tip with a clean tissue to dry.
- Blow your nose until your nostrils are clear.
- Close one nostril by gently placing your finger against the side of your nose, tilt your head slightly forward and, keeping the bottle upright, insert the nasal tip into the other nostril. Children using the nasal spray should have their head tilted slightly back. Point the tip toward the back and outer side of the nose.
- Begin to breathe in through your nose. While you are breathing, press firmly and quickly upwards with the thumb at the base while holding the white shoulder portion of the pump between your index and middle fingers. Remove the sprayer from your nose and tilt your head back for a few seconds.
- If your doctor told you to use two sprays in the same nostril, you should wait 30 seconds and then repeat steps 5 and 6 in the same nostril.
- If your doctor told you to use the spray in the other nostril, repeat steps 5 through 6 in the other nostril.
- Repeat step 3 to clean the spray tip and replace the cap and safety clip.