MIR145 gene

The MIR145 gene is a central player in many biological processes and is associated with various health conditions. It has been extensively studied and its functions have been well-documented in scientific literature.

This gene is involved in the regulation of cellular processes, including cell proliferation, differentiation, and apoptosis. It has been shown to play a role in the development of several diseases and syndromes, such as myelodysplastic syndrome and 5q minus syndrome. Changes in the MIR145 gene have been linked to genetic diseases and conditions.

There are several testing databases and resources available for the MIR145 gene. These include genetic testing services, databases like OMIM, and scientific articles and references listed on PubMed. These resources provide additional information on the gene, its variants, and its association with various diseases and conditions.

Overall, the MIR145 gene is an important gene that plays a crucial role in many biological processes. It is involved in the development of diseases and conditions, and its variants have been extensively studied in scientific literature and listed in various genetic testing databases and resources.

Health Conditions Related to Genetic Changes

Genetic changes in the MIR145 gene have been linked to various health conditions. Some of the conditions associated with genetic changes in this gene are:

  • Myelodysplastic syndrome (MDS)
  • 5q deletion syndrome

Genetic testing can identify these genetic changes in the MIR145 gene. These tests can provide valuable information for diagnosis, prognosis, and treatment options. Genetic changes in this gene can be detected through different types of tests, including:

  • Sequencing tests
  • Array-based tests

Additional scientific articles and resources related to genes and genetic changes can be found in databases such as PubMed, OMIM, and others. These resources provide information on the genes involved, associated diseases, and related health conditions.

The MIR145 gene is located on the minus strand in the 5q32 region. It is part of a larger gene called the central region of chromosome 5q. Changes in this gene have been found to play a role in the development of myelodysplastic syndrome and 5q deletion syndrome.

Genetic testing for the MIR145 gene and other related genes can be done through the use of various tests and technologies. These tests can be done through specialized laboratories, genetic testing companies, or genetic registries. Testing can provide valuable information for diagnosis, treatment, and management of genetic conditions.

References and further information on the MIR145 gene and related genetic changes can be found in scientific articles, databases, and resources dedicated to genetics and genetic testing.

5q minus syndrome

5q minus syndrome, also known as del(5q) myelodysplastic syndrome, is a rare genetic condition characterized by the deletion of a specific region of the long arm of chromosome 5. This deletion affects a gene called MIR145, among other genes in the region.

Individuals with 5q minus syndrome may experience various clinical manifestations, including bone marrow failure leading to low blood cell counts, anemia, and an increased risk of developing acute myeloid leukemia (AML). Other symptoms may include fatigue, weakness, shortness of breath, and susceptibility to infections.

Diagnosis of 5q minus syndrome involves genetic testing to identify the specific deletion in the 5q region. This can be done through various tests, including karyotyping, fluorescence in situ hybridization (FISH), and chromosomal microarray analysis (CMA). These tests can identify the chromosomal abnormalities associated with 5q minus syndrome.

In addition to testing for the MIR145 gene deletion, testing for other genes in the 5q region may also be conducted to provide a comprehensive genetic profile. These tests can help clinicians determine the prognosis and appropriate treatment options for affected individuals.

Further information about 5q minus syndrome, including scientific articles, references, and resources, can be found in databases such as PubMed, the Genetic Testing Registry, and other scientific publications. These resources provide comprehensive information on the genetic changes, associated diseases, and conditions related to 5q minus syndrome.

See Also:  RPS24 gene

Other Names for This Gene

The MIR145 gene is also known by other names:

  • miR-145
  • microRNA 145
  • hsa-miR-145
  • miRNA 145
  • MIRN145
  • MIRN145HG
  • MIRN145 host gene

These additional names for the MIR145 gene may be used in scientific articles, genetic testing, and other health-related resources. It is important to note that the names listed here are not exhaustive, and other names may exist in different databases or sources of information.

Additional Information Resources

For additional information on the MIR145 gene and related genetic tests, articles, and databases, the following resources can be consulted:

  • Genetic Testing Registry (GTR): The GTR is a central catalog of genetic tests and their associated genes. It provides information on available tests for the MIR145 gene and other genes implicated in myelodysplastic syndrome and related conditions.
  • PubMed: PubMed is a database of scientific articles in the field of health and medical research. It can be used to find publications related to the MIR145 gene, its changes, and their association with myelodysplastic syndrome.
  • Online Mendelian Inheritance in Man (OMIM): OMIM is a comprehensive database of human genes and genetic diseases. It provides detailed information on the MIR145 gene, its associated conditions, and references to scientific publications.

These resources can help researchers, healthcare professionals, and individuals interested in learning more about the MIR145 gene and its role in myelodysplastic syndrome and related conditions.

Tests Listed in the Genetic Testing Registry

The MIR145 gene, also known as “microRNA 145”, is associated with various health conditions. It is located on chromosome 5q32 and plays a role in regulating gene expression. Changes in this gene have been linked to several diseases and syndromes, including myelodysplastic syndromes.

The Genetic Testing Registry (GTR) is a central catalog of genetic tests and related information. It provides a comprehensive list of tests available for the MIR145 gene and other genes associated with conditions on chromosome 5q. These tests can help in diagnosing and managing various genetic diseases.

Tests listed in the GTR include both scientific and clinical tests. Scientific tests are primarily used for research purposes and may not be available for clinical use. Clinical tests, on the other hand, are performed in healthcare settings to aid in the diagnosis or management of specific diseases.

Additional tests listed in the GTR are related to genes and conditions that are known to be associated with the MIR145 gene. These resources can be valuable for healthcare providers and researchers looking for comprehensive information on genetic testing options.

Test Name OMIM ID Health Condition
Test A OMIM:123456 Condition A
Test B OMIM:789012 Condition B
Test C OMIM:345678 Condition C

References to these tests can be found in scientific articles, databases, and other genetic testing resources. PubMed is a commonly used reference for accessing scientific articles related to genetic testing. The Genetic Testing Registry provides links to relevant articles and databases to facilitate further research.

In conclusion, the MIR145 gene is associated with various health conditions, including myelodysplastic syndromes. The Genetic Testing Registry lists tests available for this gene and other genes on chromosome 5q. These tests can provide valuable information for diagnosing and managing genetic diseases. Additional resources, such as scientific articles and databases, offer further references and information for comprehensive genetic testing.

Scientific Articles on PubMed

PubMed is a central database for scientific articles that provides information on various genetic conditions, including the MIR145 gene. This gene, located on chromosome 5q, has been found to play a significant role in myelodysplastic syndrome. In this condition, changes in the MIR145 gene have been observed, leading to a variant that affects the health of individuals.

See Also:  Feingold syndrome

Tests for the MIR145 gene can be found in the testing catalog of PubMed. This catalog lists various genetic tests and provides information on the tests’ names, conditions they are related to, and any additional health resources or references available.

One of the resources listed in PubMed is the Online Mendelian Inheritance in Man (OMIM) database. OMIM provides valuable information on genes, diseases, and genetic conditions. It includes references to scientific articles and other relevant information.

PubMed serves as a valuable resource for scientists and researchers studying the MIR145 gene and other genes associated with myelodysplastic syndrome. It allows access to scientific articles and provides a platform for collaboration and knowledge-sharing in the field of genetics.

Catalog of Genes and Diseases from OMIM

OMIM, also known as Online Mendelian Inheritance in Man, is a comprehensive catalog of genes and genetic conditions. It provides information on various genes and their associated diseases. One such gene is the MIR145 gene, which is related to myelodysplastic syndrome.

Myelodysplastic syndrome, also called MDS, is a group of disorders characterized by abnormal development of blood cells in the bone marrow. The MIR145 gene is involved in the regulation of cell growth and division, and changes in this gene have been associated with MDS.

OMIM provides a wealth of information on genes and diseases. It lists the names of genes and their associated diseases, along with additional information such as scientific articles, references, and testing resources. The catalog also provides links to other databases and resources for further exploration.

In the case of the MIR145 gene and MDS, OMIM provides information on genetic testing resources. These tests can be used to identify changes or variants in the MIR145 gene that may be associated with the development of MDS. Additionally, OMIM provides information on central registries and resources for MDS and other related conditions.

OMIM uses a standardized nomenclature for gene and disease names, which helps to ensure consistency and clarity in the catalog. Each entry in the catalog includes a unique identifier, called an OMIM number, which can be used to quickly locate specific information.

In conclusion, OMIM’s catalog of genes and diseases provides a valuable resource for researchers, healthcare professionals, and individuals interested in genetic conditions. It includes information on the MIR145 gene and its association with myelodysplastic syndrome, along with resources for testing and additional information on related conditions.

Gene and Variant Databases

For information on the MIR145 gene, there are several gene and variant databases available that provide additional resources and references related to this gene:

  • PubMed: A scientific database that contains articles and references on genetic changes in the MIR145 gene.
  • OMIM (Online Mendelian Inheritance in Man): A comprehensive catalog of genetic diseases and conditions, including information on the MIR145 gene and its related diseases.
  • GeneTests: A registry of genetic tests for various syndromes and diseases, including tests for MIR145 gene changes.
  • GeneReviews: Provides clinical information on various genetic conditions, including those related to the MIR145 gene.

In addition to these databases, there are other central resources where you can find information on genes and variants:

  • Genes & Diseases: An online resource that lists genes linked to diseases and provides detailed information on the gene-disease associations.
  • Variant Catalog: A database that houses information on genetic variants and their associations with diseases and conditions.

These databases and resources can be valuable for genetic testing, researching related diseases and conditions, and finding further information on the MIR145 gene.

References

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