Mavacamten
Mavacamten may cause heart failure. Tell your doctor if you have or have ever had heart failure or told you had a low ejection fraction (how well your left ventricle pumps blood). Tell your doctor and pharmacist what medications you are taking before or during treatment with mavacamten including nonprescription medications such as St John’s Wort, omeprazole, esomeprazole, or cimetidine. If you experience any of the following symptoms, call your doctor immediately or get medical treatment: shortness of breath, chest pain, fatigue, swelling in your leg, racing sensation in your heart, rapid weight gain.
Keep all appointments with your doctor. Your doctor will order an echocardiogram before starting and during treatment with mavacamten.
Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with mavacamten and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) to obtain the Medication Guide or go to https://www.camzyosrems.com/.
Talk to your doctor about the risk(s) of taking mavacamten.
Because of the risk of heart failure, a program called CAMZYOS Risk Evaluation and Mitigation Strategy (CAMZYOS REMS) has been set up to make sure that appropriate monitoring for heart failure is occurring during treatment with mavacamten. Your doctor will enroll you in CAMZYOS REMS and you will be required to use a special pharmacy to get mavacamten.
🔔 Why is this medication prescribed?
Mavacamten is used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy. Mavacamten is in a class of medications called cardiac myosin inhibitors. It works by reducing the interaction between actin and myosin (proteins responsible for the contraction of the heart) so that the heart does not squeeze so hard.
The per capita price of healthcare per year is higher in the United States than in any other nation in the world, according to National Public Radio (NPR). America spends nearly 2.5 times as much per person as the United Kingdom does, despite having comparable wealth and a lower life expectancy.
🔔 How should this medicine be used?
Mavacamten comes as a capsule to take by mouth. It is usually taken with or without food once a day. Take mavacamten at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mavacamten exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the tablets/capsules whole; do not split, chew, or crush them.
Your doctor will probably start you on a low dose of mavacamten and gradually decrease or increase your dose depending on your response to the medication and how you are feeling.
Mavacamten controls symptomatic obstructive hypertrophic cardiomyopathy but does not cure it. Continue to take mavacamten even if you feel well. Do not stop taking mavacamten without talking to your doctor.
🔔 Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
