What to Know About Intravascular Large B-Cell Lymphoma (IVLBCL)

Intravascular large B-cell lymphoma is a rare type of non-Hodgkin’s lymphoma. Its symptoms can vary greatly, making it difficult to diagnose. This type of lymphoma is aggressive, and outlook for people with this disease is typically poor.

Intravascular large B-cell lymphoma (IVLBCL) is a type of non-Hodgkin’s lymphoma. In IVLBCL, lymphoma cells accumulate within blood vessels, which can affect organ function.

IVLBCL is very rare. It’s been estimated to occur in fewer than 0.5 out of one million individuals each year.

Below, we’ll cover more details about IVLBCL, including its symptoms and how it’s diagnosed and treated. Continue reading to discover more.

IVLBCL is a rare subtype of diffuse large B-cell lymphoma. Diffuse large B-cell lymphomas such as IVLBCL are an aggressive type of non-Hodgkin’s lymphoma.

IVLBCL is characterized by lymphoma cells that build up in the small- and medium-sized blood vessels in your body (small veins and arteries). This accumulation of cells can eventually cause blockages within these blood vessels.

Uninterrupted blood flow is essential for the organs and tissues of your body to function. Because of this, the effects of IVLBCL can lead to serious complications in the affected organs.

While IVLBCL can affect any part of your body, the most commonly affected area is the central nervous system (CNS), which includes your brain and spinal cord. Other areas that are commonly involved include your skin and bone marrow.

Can intravascular large B-cell lymphoma (IVLBCL) be cured?

It’s possible for some people with IVLBCL to reach a complete remission. This is when no signs of cancer can be found in the body after treatment. But it’s still possible for IVLBCL to come back after treatment.