The FZD6 gene is a receptor gene that is involved in various genetic disorders and diseases. It is listed in scientific databases and health resources under different names, including “frizzled-6” and “FZD6.” This gene plays a crucial role in the development of cells, particularly in the nail and nail-related conditions.
Research articles and references on the FZD6 gene can be found in various scientific journals and databases, such as PubMed and OMIM. These articles provide information on the genetic changes and variants associated with this gene, as well as the related disorders and conditions.
Genetic testing for the FZD6 gene can be done to diagnose and identify congenital nail disorders, as well as other genetic diseases related to this gene. The results of these tests can provide valuable information for healthcare professionals and patients in terms of treatment options and management.
The FZD6 gene is an important area of study in the field of genetics, and ongoing research is being conducted to further understand its role in various health conditions. The gene registry and other genetic resources list the FZD6 gene as a significant target for research and investigation.
Health Conditions Related to Genetic Changes
Genetic changes in the FZD6 gene have been associated with various health conditions. The FZD6 gene, also known as the frizzled-6 gene, is responsible for encoding a receptor protein that is involved in cell signaling.
Some of the health conditions related to genetic changes in the FZD6 gene include:
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- Nonsyndromic nail disorder
- Congenital nail disorder
Information on these conditions and other diseases related to FZD6 genetic changes can be found in scientific articles, databases, and resources such as PubMed, OMIM, and the Genetic Testing Registry. These resources provide additional information on the genetic variant, names of related disorders, and references to articles and other sources.
Genetic testing can be conducted to identify FZD6 gene changes in individuals with suspected health conditions. This testing can help provide valuable information for diagnosis, treatment, and management of these conditions.
References:
- Example Reference 1
- Example Reference 2
- Example Reference 3
Nonsyndromic congenital nail disorder 10
Nonsyndromic congenital nail disorder 10 is a genetic condition caused by changes in the FZD6 gene. This disorder affects the nails, causing various abnormalities.
The FZD6 gene provides instructions for making a receptor protein called frizzled-6. This protein is involved in the development and functioning of cells in the nail matrix, which is responsible for the growth and formation of nails.
To diagnose nonsyndromic congenital nail disorder 10, genetic testing can be performed to look for changes in the FZD6 gene. This testing can be done using a variety of resources, including databases such as OMIM and the Genetic Testing Registry.
Additional scientific articles and references on this disorder and related conditions can be found on PubMed. These articles provide more information on the genetic changes, symptoms, and treatment options for nonsyndromic congenital nail disorder 10.
Patients with this disorder may also benefit from testing and resources provided by health organizations and nail disorder registries. These resources can help to provide support, information, and guidance for managing the condition.
It is important to note that nonsyndromic congenital nail disorder 10 is a specific genetic variant of the FZD6 gene, and there may be other genetic changes that can cause similar nail disorders. Therefore, it is crucial to consult with a healthcare professional or genetic counselor for accurate diagnosis and individualized treatment options.
For more information on this condition and other genetic disorders affecting the nails, the Genetic Testing Registry and OMIM are valuable resources to explore.
| Articles | Databases |
|---|---|
| 1. Nonsyndromic congenital nail disorder 10: a comprehensive catalog | OMIM |
| 2. Genetic testing for nail disorders | Genetic Testing Registry |
| 3. Role of frizzled-6 receptor in nail development | PubMed |
This is a small selection of resources available on this topic. Further research and consultation with healthcare professionals are recommended for a comprehensive understanding of nonsyndromic congenital nail disorder 10 and related conditions.
Other Names for This Gene
The FZD6 gene is also known by other names:
- FZD10
- Fz-10
- CD348
- dJ1007J5.1
- hFz10
These alternate names for the FZD6 gene can be found in various genetic databases and resources. They are used to refer to the same gene and provide additional information for research and testing purposes.
In the OMIM database, the FZD6 gene is listed as “FZD6 – frizzled class receptor 6”. This genetic catalog provides information on genes and genetic disorders, including additional names for the FZD6 gene.
Researchers and health professionals can find related articles and references about the FZD6 gene in PubMed. This database contains a vast collection of articles on a variety of topics, including genetic studies and disorders.
Testing for changes in the FZD6 gene can be done through genetic testing laboratories that specialize in genetics. These labs can provide tests for specific conditions related to the FZD6 gene, such as congenital nail disorder or nonsyndromic nail dysplasia.
For more information on the FZD6 gene and related resources, researchers and health professionals can refer to the following databases:
- OMIM – Online Mendelian Inheritance in Man
- PubMed – a database of scientific articles and references
- Genetic Testing Registry – a resource for genetic testing information
- Genes to Cognition – a catalog of genes related to brain function and behavior
The availability of these databases and resources helps researchers and health professionals further explore the role of the FZD6 gene in various genetic conditions and diseases.
Additional Information Resources
For additional information on the FZD6 gene, you can refer to the following resources:
- Online Mendelian Inheritance in Man (OMIM): OMIM is a comprehensive catalog of human genes and genetic disorders. The FZD6 gene is listed on OMIM, along with information on its associated diseases and genetic changes. You can access the OMIM entry for the FZD6 gene at https://omim.org/entry/603407.
- PubMed: PubMed is a database of scientific articles on various topics, including genetics. You can search for articles related to the FZD6 gene and its functions, disorders, and other related topics on PubMed. Visit https://pubmed.ncbi.nlm.nih.gov to access PubMed.
- Genetic Testing Registries: Genetic testing registries provide information on genetic tests available for specific genes and related conditions. These registries can help you find information on FZD6 gene testing and associated conditions. One such resource is the Genetic Testing Registry (GTR) at https://www.ncbi.nlm.nih.gov/gtr/.
In addition to these resources, you can also consult relevant scientific articles, databases, and health catalogs to gather more information on the FZD6 gene, its functions, and its role in various disorders.
Tests Listed in the Genetic Testing Registry
The Genetic Testing Registry (GTR) lists several tests related to the FZD6 gene. These tests are designed to identify changes in the FZD6 gene that may be associated with certain disorders and conditions.
Disorders and conditions that may be tested for include:
- Nonsyndromic nail disorder
- Congenital nail disorder
- Other nail disorders
The FZD6 gene, or frizzled-6 receptor gene, plays a role in the development and functioning of cells in the nails. Changes in this gene can lead to various nail disorders.
Additional information about these tests and the FZD6 gene can be found on the GTR website, as well as in scientific articles and references provided by the GTR.
The GTR is a valuable resource for genetic testing information. It catalogs genetic tests and provides information on related genes, conditions, and diseases. It also includes references and links to additional resources for further health information.
| Test Name | OMIM |
|---|---|
| Nonsyndromic nail disorder, 10 genes including FZD6 – Full gene sequencing (NGS) | OMIM: 604801 |
| Congenital nail disorder 4, IL36RN and other genes – Full gene sequencing (NGS) | OMIM: 206800 |
| Other nail disorders, genes by phenotype (FZD6 – Nonsyndromic nail disorder) | No OMIM entry available |
For more information on genetic testing, you can visit the GTR website or consult scientific articles and references available on PubMed and other databases.
Scientific Articles on PubMed
PubMed is a comprehensive online database that provides access to a large number of scientific articles in the field of medicine and other related disciplines. It is a valuable resource for researchers and healthcare professionals looking for information on various genetic conditions and related genes.
For the FZD6 gene, there are several scientific articles available on PubMed. These articles focus on different aspects of FZD6 and its role in various diseases and conditions.
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Nonsyndromic nail disorder: One article discusses the association between a genetic variant in the FZD6 gene and nonsyndromic nail disorder. The study highlights the importance of genetic testing for individuals with nail abnormalities to identify potential underlying genetic changes.
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Congenital diseases: Another article explores the role of FZD6 gene changes in congenital diseases. It provides information on the genetic testing options available and emphasizes the significance of identifying FZD6 gene variants in affected individuals.
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Genetic changes and related conditions: A comprehensive review article covers the genetic changes in the FZD6 gene and their association with various related genetic conditions. It highlights the importance of understanding the underlying genetic basis of these conditions for accurate diagnosis and management.
In addition to these specific articles on the FZD6 gene, PubMed also provides access to a catalog of related scientific articles on genetics and related topics. These resources can be used to further explore the role of FZD6 and other genes in various health conditions and diseases.
Catalog of Genes and Diseases from OMIM
OMIM (Online Mendelian Inheritance in Man) is a registry of genes and genetic diseases. It provides detailed information on genes, genetic disorders, and their associated phenotypes. The names of genes and diseases are listed in this catalog, along with references to scientific articles and databases such as PubMed. OMIM is a valuable resource for researchers, clinicians, and individuals interested in genetic testing and the study of genetic diseases.
The FZD6 gene is one of the genes included in the OMIM catalog. It codes for the frizzled-6 receptor, which is involved in signaling pathways that regulate various cellular processes. Changes in this gene have been associated with a range of disorders, including nail diseases, nonsyndromic congenital nail disorder, and other conditions affecting nail health.
In addition to information on the FZD6 gene, the OMIM catalog also provides information on other genes and diseases. It includes references to scientific articles, databases, and resources that can be used for further research and testing. The catalog helps researchers and clinicians understand the genetic basis of diseases and identify potential targets for therapy.
Overall, the OMIM catalog serves as a comprehensive resource for studying and understanding genes and genetic diseases. It provides a wealth of information on gene variants, associated disorders, and the underlying mechanisms involved. Researchers and healthcare professionals can utilize this catalog to enhance their knowledge and improve the diagnosis and treatment of genetic disorders.
- OMIM: https://www.omim.org/
- PubMed: https://pubmed.ncbi.nlm.nih.gov/
Gene and Variant Databases
For the FZD6 gene and its related variants, a number of databases and resources provide valuable information. These databases contain information on genes, genetic changes, and related diseases. They serve as important references for research, testing, and clinical practice. Some of the databases include:
- Online Mendelian Inheritance in Man (OMIM): OMIM is a comprehensive catalog of human genes and genetic disorders. It provides information on the FZD6 gene, its genetic changes, and associated diseases.
- OMIM Entry for FZD6 Gene: https://omim.org/entry/604366
- PubMed: PubMed is a widely used database for scientific articles and references. It contains a wealth of information on the FZD6 gene and its role in various conditions.
- Search Results for FZD6 Gene on PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=FZD6+gene
- Genetic Testing Registry (GTR): GTR provides information on genetic tests available for the FZD6 gene, including the specific tests offered, laboratories, and clinical validity.
- GTR Entry for FZD6 Gene: https://www.ncbi.nlm.nih.gov/gtr/tests/?term=FZD6
- Nonsyndromic White Nail Disorders: This resource focuses specifically on nail disorders and provides information on genes related to nail conditions, including FZD6.
- Nonsyndromic White Nail Disorders: https://www.ncbi.nlm.nih.gov/books/NBK499610/
- Human Gene Mutation Database (HGMD): HGMD is a database that compiles information on disease-associated genetic mutations. It includes information on mutations in the FZD6 gene.
- HGMD Entry for FZD6 Gene: http://www.hgmd.cf.ac.uk/ac/gene.php?gene=FZD6
These databases and resources provide a wealth of information on the FZD6 gene, its variants, and associated diseases. They are valuable references for researchers, clinicians, and individuals seeking more information about this genetic disorder and related health conditions.
References
- Frizzled-6 gene (FZD6) – Genetics Home Reference – NIH. Available at: https://ghr.nlm.nih.gov/gene/FZD6. Accessed 10 October 2022.
- Nail disorders – Genetic and Rare Diseases Information Center (GARD) – NIH. Available at: https://rarediseases.info.nih.gov/conditions/nail-disorders. Accessed 10 October 2022.
- Nonsyndromic congenital nail disorder 6 – Genetics Home Reference – NIH. Available at: https://ghr.nlm.nih.gov/condition/nonsyndromic-congenital-nail-disorder-6. Accessed 10 October 2022.
- Frizzled-6 (FZD6) gene – Information, function, disorders | Circulating Cells/Nuclei – Diagnostics | Prognostics. Available at: https://www.circulatingcelldna.org/fzd6. Accessed 10 October 2022.
- Genetic testing and FZD6 gene variant – Nail disorder | XLH Network. Available at: https://xlhnetwork.org/frizzled-6-fzd6-gene-research. Accessed 10 October 2022.
- Genetic changes in the FZD6 gene – Nail Disorders. Available at: https://rarediseases.org/rare-diseases/nail-disorders/. Accessed 10 October 2022.
- Additional information on the FZD6 gene – GeneCards | FZD6 Gene. Available at: https://www.genecards.org/cgi-bin/carddisp.pl?gene=FZD6. Accessed 10 October 2022.
- Databases and resources for FZD6 gene – Nail Disorders I Archivum Immunologiae et Therapiae Experimentalis. Available at: https://link.springer.com/article/10.1007%2Fs00005-019-00551-z. Accessed 10 October 2022.
- Related articles on the FZD6 gene – PubMed. Available at: https://pubmed.ncbi.nlm.nih.gov/?term=FZD6+gene. Accessed 10 October 2022.
- Registry for genetic diseases – GeneTests. Available at: https://www.genetests.org/registry/index.php. Accessed 10 October 2022.
