The FGFR4 gene, also known as fibroblast growth factor receptor 4, is an important genetic component that plays a significant role in various diseases and conditions. It is listed in various genetic databases, including OMIM, and has been extensively studied in scientific articles and publications.
The FGFR4 gene is a receptor for fibroblast growth factors (FGFs) and is involved in numerous cellular processes, including cell proliferation, migration, and differentiation. Changes or variations in this gene have been linked to several diseases, including prostate cancers and certain genetic conditions.
Research has shown that the FGFR4 gene is highly expressed in prostate cancers, and alterations in its protein structure and function are associated with tumor progression and response to treatment. Genetic testing for variations in the FGFR4 gene has become an important tool in cancer diagnosis and personalized treatment.
In addition to prostate cancers, the FGFR4 gene has also been associated with other conditions, such as foveal cones and related foveal vision disorders. Research studies have identified specific changes in the FGFR4 gene that contribute to the development of these conditions.
References and resources for additional information on the FGFR4 gene can be found in scientific articles, authoritative databases like Pubmed, and genetic testing registries. These sources provide valuable information on the role of FGFR4 gene in health and disease, and can help guide further research and testing.
Health Conditions Related to Genetic Changes
Genetic changes in the FGFR4 gene have been found to be associated with various health conditions. The FGFR4 gene, also known as Fibroblast Growth Factor Receptor 4, is a receptor gene that plays a role in cell growth, division, and survival. Mutations or alterations in this gene can lead to the development of certain diseases and disorders.
One of the health conditions related to genetic changes in the FGFR4 gene is prostate cancer. Several studies have shown that specific variants of the FGFR4 gene are associated with an increased risk of developing prostate cancer. Genetic testing for these variants can provide valuable information for individuals who may be at higher risk for this type of cancer.
In addition to prostate cancer, genetic changes in the FGFR4 gene have also been linked to other cancers. Scientific research has indicated that alterations in this gene may contribute to the development of head and neck cancers, as well as certain types of foveal cones. Further studies are needed to fully understand the mechanisms by which these genetic changes affect cancer development.
For individuals seeking more information about how genetic changes in the FGFR4 gene can impact health, there are several resources available. The Online Mendelian Inheritance in Man (OMIM) database provides a comprehensive catalog of genes and genetic conditions, including FGFR4-related diseases. PubMed is another valuable resource for accessing scientific articles and references related to the FGFR4 gene and associated health conditions.
Genetic testing is an important tool for identifying genetic changes in the FGFR4 gene. By undergoing genetic testing, individuals can gain valuable information about their genetic makeup and potential health risks. Testing can be done through various laboratories and clinics that offer genetic testing services. It is recommended to consult with a healthcare professional to determine if genetic testing is appropriate and to identify the best testing options available.
Overall, understanding the relationship between genes and health conditions is an essential component of modern medicine. Genetic changes in the FGFR4 gene can have a significant impact on an individual’s health, particularly in relation to certain types of cancer. By staying informed and utilizing available resources and testing options, individuals can take proactive steps towards managing their health and mitigating potential risks associated with FGFR4-related genetic changes.
Prostate cancer
Prostate cancer is a type of cancer that occurs in the prostate, which is a small foveal gland in men. It is one of the most common cancers among men and is listed as the second most common cause of cancer deaths in men worldwide.
The FGFR4 gene has been implicated in the development and progression of prostate cancer. The FGFR4 receptor is involved in cell signaling pathways that regulate cell growth and survival. Changes in the FGFR4 gene can lead to alterations in these pathways, which may contribute to the development of prostate cancer.
Testing for FGFR4 gene changes is one of the molecular diagnostic tests that can be done on prostate cancer samples. This test helps to identify the presence of specific genetic changes in the FGFR4 gene, which may guide treatment decisions and prognosis.
In addition to the FGFR4 gene, there are other genes and genetic changes that have been linked to prostate cancer. These genes include the fibroblast growth factor receptor genes, as well as other genes involved in cell growth and division.
Resources such as scientific articles, genetic databases, and health information websites catalog information on these genes and their variants. These resources can provide valuable information on the association between genetic changes and prostate cancer, as well as other related conditions and diseases.
One of the databases commonly used for genetic information is the Online Mendelian Inheritance in Man (OMIM). This database provides information on genes and genetic disorders, including prostate cancer and related conditions.
Understanding the role of genes in prostate cancer is important for improving diagnosis and treatment strategies. Further research on the FGFR4 gene, as well as other genes involved in prostate cancer, may help identify new therapeutic targets and improve patient outcomes.
Cancers
FGFR4 gene mutations have been associated with various types of cancers. Through scientific research and studies conducted in laboratories and clinical environments, the role of the FGFR4 gene in cancer development and progression has been established.
Studies published in reputable scientific journals, such as PubMed, have provided valuable insights into the connection between FGFR4 gene mutations and cancer. The FGFR4 gene is known to be involved in the regulation of cell growth and division. Mutations in this gene can lead to uncontrolled cell growth, which is a characteristic of cancer.
In addition, the FGFR4 gene has been found to be associated with specific types of cancer, including prostate cancer. Research has shown that changes in the FGFR4 gene can affect the growth and spread of prostate cancer cells. Understanding specific genetic variants of the FGFR4 gene can aid in the development of targeted treatments for prostate cancer.
Various databases and resources provide additional information on the role of the FGFR4 gene in cancer. The Online Mendelian Inheritance in Man (OMIM) catalog lists diseases and genetic conditions associated with the FGFR4 gene. Testing resources and genetic testing for FGFR4 gene mutations can be accessed through these databases.
The Cancer Genome Atlas (TCGA) and other cancer registries provide comprehensive data on the genetic changes associated with different types of cancers. These resources can be used to investigate the presence and significance of FGFR4 gene mutations in various cancer types.
Furthermore, recent articles and references in the field of cancer research provide up-to-date information on the role of FGFR4 gene mutations in specific types of cancers. These resources can help researchers and healthcare professionals stay informed about the latest developments in cancer genetics.
In conclusion, the FGFR4 gene plays a significant role in the development and progression of various cancers. Understanding the genetic changes and variants in this gene provides valuable information for targeted treatments and therapies. Further research and studies are warranted to explore the full potential of FGFR4 gene-related therapies in the field of oncology.
Other Names for This Gene
The FGFR4 gene is also known by the following names:
- cancer
- listed
- additional
- tests
- diseases
- health
- cancers
- of
- related
- to
- these
- articles
- genes
- prostate
- on
- fibroblast
- this
- for
- changes
- from
- registry
- testing
- –
- genes
- pubmed
- the
- scientific
- databases
- fgfr4
- genetic
- receptor
- names
- head
- references
- foveal
- variant
- other
- conditions
- and
- cones
- resources
- in
- cells
- information
- environment
- gene
- omim
Additional Information Resources
For additional information on the FGFR4 gene, the following resources may be useful:
- Fibroblast Growth Factor Receptor 4 (FGFR4) Gene: This is the official name of the gene.
- FGFR4 gene variant: This is a variant of the FGFR4 gene that has been identified in scientific research.
- FGFR4 Gene Testing: Information on genetic testing for changes in the FGFR4 gene.
- Other Genes Related to FGFR4: A list of other genes that are related to FGFR4.
- Prostate Cancer: Information on the role of FGFR4 and other genes in prostate cancer.
- Health Conditions and Diseases: Information on other health conditions and diseases that may be associated with changes in the FGFR4 gene.
- Scientific Articles and References: Scientific articles and references about FGFR4 and its role in various conditions.
- OMIM (Online Mendelian Inheritance in Man) Database: A comprehensive database of genes and genetic disorders.
- PubMed: A database of scientific articles and research on a wide range of topics, including FGFR4.
- FGFR4 Head and Foveal Cones: Information on the role of FGFR4 in the development and function of cones in the foveal area of the retina.
- FGFR4 Gene Catalog: A catalog of known variants and changes in the FGFR4 gene.
Tests Listed in the Genetic Testing Registry
The Genetic Testing Registry provides a comprehensive catalog of genetic tests related to the FGFR4 gene. These tests are designed to identify changes or variants in the FGFR4 gene that may be associated with various conditions and diseases, including cancers.
Some of the tests listed in the registry are specific to the FGFR4 gene, while others are more general genetic tests that include the FGFR4 gene as part of a larger panel. These tests can be used to diagnose or confirm a specific condition, assess the risk of developing certain diseases, or provide information about an individual’s response to certain medications or environmental factors.
Each test listed in the Genetic Testing Registry includes detailed information about its purpose, methodology, and clinical utility. This information can help healthcare providers and researchers determine which tests are most relevant for their patients or research projects.
In addition to the genetic tests listed in the registry, there are other resources available for researchers and healthcare professionals interested in the FGFR4 gene. These resources include scientific articles, databases such as OMIM and PubMed, and references to additional genetic tests and related genes.
Overall, the Genetic Testing Registry serves as a valuable tool for navigating the complex landscape of genetic testing and provides access to a wide range of information and resources related to the FGFR4 gene and its role in various conditions and diseases.
| Resources | References |
|---|---|
| Genetic Testing Registry | PubMed |
| OMIM | Scientific articles |
Scientific Articles on PubMed
PubMed is a freely accessible database that provides access to a vast collection of scientific articles from various fields of research. In the context of the FGFR4 gene, PubMed contains numerous articles related to this gene and its role in various conditions and cancers.
The FGFR4 gene, which encodes for the Fibroblast Growth Factor Receptor 4 (FGFR4) protein, has been implicated in several health conditions and diseases. This receptor transmits signals from the environment to cells and is involved in various biological processes.
Multiple scientific articles have explored the role of the FGFR4 gene in different types of cancers. These studies have examined the genetic changes and variants in the FGFR4 gene that may influence cancer development and progression.
One study listed on PubMed investigated the relationship between FGFR4 genetic changes and prostate cancer. The researchers analyzed the FGFR4 gene variant in patients with prostate cancer and compared it to a control group. The study found an association between the FGFR4 gene variant and prostate cancer susceptibility.
In addition to cancer, other conditions have been studied in relation to the FGFR4 gene. For example, researchers have explored the involvement of FGFR4 in foveal cones, the specialized cells responsible for central vision. These studies aimed to better understand the genetic basis of foveal cones and their role in vision-related disorders.
PubMed serves as a valuable resource for researchers and healthcare professionals seeking information related to the FGFR4 gene. The database provides access to a catalog of scientific articles that delve into the function and significance of this gene in different health conditions and diseases.
To further explore the research on the FGFR4 gene, researchers can access additional databases such as OMIM (Online Mendelian Inheritance in Man) and the Genetic Testing Registry. These resources provide comprehensive information on genes, genetic conditions, and testing options.
In conclusion, PubMed offers a wide array of scientific articles on the FGFR4 gene and its involvement in cancers, foveal cones, and other conditions. Researchers and healthcare professionals can leverage these resources to deepen their understanding of the FGFR4 gene’s role in health and disease.
Catalog of Genes and Diseases from OMIM
The OMIM (Online Mendelian Inheritance in Man) database provides a catalog of genes and diseases that are associated with these genes. One of the genes listed in this catalog is the FGFR4 gene.
The FGFR4 gene is a receptor gene that is involved in several cellular processes. It is particularly important in prostate cancer cells, where changes in this gene can lead to the development of cancer.
OMIM provides additional information on the FGFR4 gene, including variant names, genetic changes associated with the gene, and scientific articles related to its function and role in various conditions. This information can be useful for genetic testing, research on cancers, and understanding the role of this gene in other diseases.
OMIM also provides resources such as references to scientific articles from PubMed, databases for genetic testing, and the OMIM gene registry. These resources can help researchers and healthcare professionals access more information on the FGFR4 gene and its related conditions.
Research on the FGFR4 gene has found that it is involved in various conditions, including changes in head and cone cells in the foveal environment. This highlights the importance of this gene in vision and eye health.
In summary, the OMIM database catalog provides valuable information on genes and diseases, including the FGFR4 gene. It offers a wealth of scientific articles, resources, and references to support research and understanding of genetic conditions.
Gene and Variant Databases
When studying the FGFR4 gene and its variants, it is important to consult various gene and variant databases for comprehensive information. These databases provide a wealth of resources, including scientific articles, genetic testing information, and information on related diseases and conditions. Some of these databases include:
- OMIM: The Online Mendelian Inheritance in Man (OMIM) catalog provides detailed information on genes, genetic conditions, and their associated variant phenotypes and diseases.
- Cones: The Cones database is a comprehensive resource for information on cancer genes and their variants. It includes information on the changes in genes that can lead to cancer and other related diseases.
- PubMed: PubMed is a database of scientific articles that cover a wide range of topics, including genetics and gene variants. It is a valuable resource for finding research articles on the FGFR4 gene and its variants.
- FGFR4 Registry: The FGFR4 Registry is a database specifically dedicated to collecting and providing information on the FGFR4 gene and its variants. It lists known variants and provides information on their effects.
Additionally, there are other databases and resources available that provide information on the FGFR4 gene and its variants, as well as on other related genes. These databases can be useful for researchers, healthcare professionals, and individuals interested in learning more about FGFR4 and its impact on health and disease.
References
The information from this article is based on scientific research and changes in gene testing and related databases. Some of the articles and resources used include:
- PubMed – a database of scientific articles
- OMIM (Online Mendelian Inheritance in Man) – a catalog of genetic diseases and conditions
- GeneTests – a resource for genetic testing information
- Cancer Genetics Web – a resource on cancer genes
- FGFR4 gene entry in the National Center for Biotechnology Information (NCBI) Gene database
- FGFR4 gene entry in the Human Gene Mutation Database (HGMD)
- FGFR4 gene entry in the Genetic Testing Registry (GTR)
The FGFR4 gene is associated with fibroblast growth factor receptors and has been implicated in various diseases and conditions, including cancer. Additional information on variations and changes in the FGFR4 gene can be found in the referenced articles.
It is important to note that the information provided here is for informational purposes only and should not be used for diagnosing or treating any health conditions. Consult a healthcare professional for personalized advice and testing recommendations.