Edaravone Oral

Edaravone is used to treat amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease; a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken). Edaravone is in a class of medications called antioxidants. It may work to slow the nerve damage associated with the worsening of ALS symptoms.

🔔 How should this medicine be used?

Edaravone comes as a suspension (liquid) to take by mouth or through a feeding tube. It is usually taken in the morning on an empty stomach. If you have eaten a high-fat meal (800-1000 calories, 50% fat) the night before, you should wait at least 8 hours after eating to take edavarone. If you have eaten a low-fat meal (400-500 calories, 25% fat), you should wait at least 4 hours after eating to take edavarone. If you have eaten a meal supplement such as a protein drink (250 calories), you should wait at least 2 hours before taking edavarone. After taking edaravone, you should wait at least one hour before eating or drinking anything besides water. Take edaravone at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take edaravone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Initially, it is usually given once a day for the first 14 days of a 28-day cycle. After the first cycle, it is given once a day for the first 10 days of a 28-day cycle. Your doctor will decide how often you are to receive edaravone based on your body’s response to this medication.

Before opening the bottle, turn edaravone upside down and shake vigorously for at least 30 seconds. The dose of edaravone should only be measured with the oral syringe that comes with it. Edaravone oral suspension can also be placed in nasogastric (NG) or percutaneous endoscopic gastrostomy (PEG) tubes made of silicone or PVC. After administering edaravone through a feeding tube, the feeding tube should be flushed with at least 1 ounce (30 mL) of water using a catheter-tip syringe.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

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