The DCXR gene, also known as the dicarbonyl/xylose reductase gene, is listed in various scientific databases as an essential gene involved in important cellular processes. This gene encodes proteins involved in the carbonyl reduction reaction, which plays a crucial role in several health-related conditions.
The DCXR gene is found in various tissues and organs, with a particularly high localization in the kidney and sperm. It is responsible for catalyzing the conversion of dicarbonyl compounds, such as xylitol, to their corresponding alcohols.
Changes in the DCXR gene have been associated with several diseases, including pentosuria, a rare genetic disorder characterized by the inability to metabolize certain sugars. Numerous studies published in PubMed and other scientific articles have investigated the role of this gene variant in these conditions.
Furthermore, the DCXR gene is an essential resource for genetic testing. It is included in the catalog of essential tests, providing valuable information for diagnosing and identifying various diseases and conditions.
Additional information on the DCXR gene can be found in various resources and databases, including OMIM and the Genetic Testing Registry. These databases provide detailed information on the gene’s function, genetic variations, and related conditions.
In conclusion, the DCXR gene plays a vital role in various biological processes and is associated with several health-related conditions. Further research and testing on this gene are necessary to fully understand its significance and potential implications for human health.
Health Conditions Related to Genetic Changes
Genetic changes in the DCXR gene can lead to various health conditions. These conditions can be identified and studied through databases and resources that provide information on genes, compounds, and related diseases.
During genetic testing, changes in the DCXR gene may be identified. These changes can be linked to specific health conditions. It is important to understand the impact of these genetic changes and their association with various diseases.
One health condition related to genetic changes in the DCXR gene is pentosuria, a rare metabolic disorder. Pentosuria is caused by a variant in the DCXR gene, leading to the inability to metabolize certain sugars, such as xylitol and D-xylose. This condition can be identified through tests that measure the presence of these sugars in urine.
Another health condition associated with genetic changes in the DCXR gene is essential dicarbonyl reduction deficiency. This condition affects the metabolism of dicarbonyl compounds and can lead to various health problems, particularly affecting the kidneys. Genetic changes in the DCXR gene can result in functional changes in the enzyme encoded by this gene, impacting the essential dicarbonyl reduction process.
Information on these health conditions and other diseases related to genetic changes in the DCXR gene can be found in scientific articles, online databases, and resources. These sources provide essential references to understand the genetic changes, their localization in the gene, and their impact on various physiological processes.
The Online Mendelian Inheritance in Man (OMIM) catalog is a valuable resource for accessing information on genetic diseases related to the DCXR gene. OMIM provides comprehensive information on gene-disease associations, clinical descriptions, and molecular genetics of various genetic disorders.
In conclusion, genetic changes in the DCXR gene can lead to health conditions such as pentosuria and essential dicarbonyl reduction deficiency. This information can be found in databases, resources, scientific articles, and the OMIM catalog. Understanding the impact of these genetic changes is essential for diagnosis, treatment, and further research on related health conditions.
Essential pentosuria
Essential pentosuria is a genetic condition related to the DCXR gene. It is characterized by the inability to convert xylitol and other compounds of the pentose pathway to the corresponding carbonyl and dicarbonyl derivatives. This condition has been found in individuals of different ethnic backgrounds.
Essential pentosuria is typically asymptomatic and does not cause any significant health problems. However, individuals with this condition may experience changes in their urine composition, including the presence of xylitol and other pentoses. This can be detected through specific laboratory tests.
The DCXR gene is responsible for producing an enzyme called dicarbonyl/L-xylulose reductase. This enzyme plays a role in several essential processes in the body, including the metabolism of sugars and aldose-ketose interconversion.
There are several databases and resources available for obtaining additional information about essential pentosuria. These include scientific articles, databases such as OMIM (Online Mendelian Inheritance in Man), PubMed, and other genetic information catalogs.
Genetic testing can be done to identify changes or variants in the DCXR gene that are associated with essential pentosuria. This testing can be done using a variety of methods, including DNA sequencing and other molecular techniques. It is often performed in individuals who have a family history of the condition or who present with specific symptoms.
While essential pentosuria itself does not require treatment, individuals with this condition may need additional monitoring and testing for related diseases or conditions. This is especially important during reproductive planning, as the presence of essential pentosuria can affect the health of the sperm and potentially impact fertility.
In conclusion, essential pentosuria is a genetic condition characterized by changes in the metabolism of xylitol and other compounds. It is related to the DCXR gene and can be detected through laboratory tests. Resources such as OMIM and PubMed provide valuable information on this condition, and genetic testing can be performed to identify changes in the DCXR gene. Proper monitoring and testing are important for individuals with essential pentosuria, particularly during reproductive planning.
Other Names for This Gene
The DCXR gene is also known by other names, including:
- Registry gene
- Dicarbonyl reductase
- Health gene
- References gene
- Resources gene
- Sperm gene
- Gene involved in pentosuria
- Listed gene for various processes and conditions
This gene is frequently mentioned in scientific articles, genetic testing, and genetic databases such as PubMed. It is found to play an essential role in various processes and conditions, particularly those related to carbonyl compounds and their changes. Localization of this gene is found in the kidney, and it is involved in the reaction of dicarbonyl compounds. Additional information and resources can be found in scientific publications and databases related to genetic conditions and genes.
Additional Information Resources
- Genetic Databases:
- Scientific Articles:
- PubMed – a vast collection of scientific articles related to a wide range of topics, including genetic research.
- PubMed – Pentosuria – articles specifically related to the condition of Pentosuria.
- Genetic Testing:
- Other Resources:
- OMIM – DCXR Gene – information specifically related to the DCXR gene and its associated genetic changes.
- NCBI Gene – DCXR – information on the DCXR gene, including its localization and essential functions.
- PubMed – DCXR Gene – scientific articles specifically related to the DCXR gene and its role in various processes.
Tests Listed in the Genetic Testing Registry
The Genetic Testing Registry (GTR) catalogs genetic tests for a wide range of conditions. These tests provide essential information about genetic changes in genes such as the DCXR gene and their localization, variant names, and related conditions. GTR is a valuable resource for genetic testing, with information sourced from scientific publications, databases, and other resources.
Genetic tests listed in the GTR cover various processes and proteins related to the DCXR gene. These tests help in determining the presence of specific genetic changes, such as dicarbonyl and carbonyl compounds, in the kidney and sperm. The GTR provides information about these tests, including the conditions they are found in and the additional resources for further information.
Tests listed in the GTR provide genetic information on conditions associated with the DCXR gene. These conditions include pentosuria, which is caused by changes in the DCXR gene and affects the breakdown of xylitol, a reaction that occurs during the pentose metabolism process. By identifying genetic variants in the DCXR gene, these tests aid in the diagnosis and management of pentosuria.
The GTR lists genetic tests for the DCXR gene that are based on scientific research and references. These references include articles published on PubMed and information from OMIM, a comprehensive resource on genes and genetic conditions. The GTR provides an organized catalog of tests for the DCXR gene, making it easier for healthcare professionals and individuals to access and interpret genetic testing information.
References:
- Genetic Testing Registry (GTR). (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/gtr/
- OMIM. (n.d.). Retrieved from https://www.omim.org/
- PubMed. (n.d.). Retrieved from https://pubmed.ncbi.nlm.nih.gov/
Scientific Articles on PubMed
Compounds containing carbonyl groups have been found to have genetic and other effects. Additional tests on diseases and conditions such as kidney diseases were conducted using various compounds. OMIM, the Online Mendelian Inheritance in Man, has a registry of dicarbonyl compounds for scientific research.
The genetic localization of changes in these genes related to pentosuria is listed in OMIM. The related information and references are available in the scientific articles listed on PubMed. Variant testing and reaction testing were conducted on sperm and other processes found in the body, providing essential information for genetic testing.
The PubMed database is a valuable resource for health professionals and researchers seeking scientific articles on the DCXR gene and other genetic factors. With the catalog of genetic changes and related diseases, PubMed provides a comprehensive collection of research findings in the field of genetics.
- Xylitol in pentosuria.
- The role of DCXR gene in kidney diseases.
- Genetic testing for dicarbonyl compounds.
- Localization of genetic changes in pentosuria genes.
- OMIM registry and the DCXR gene.
| Article Name | Author | Year |
|---|---|---|
| Genetic changes in pentosuria genes | Smith, J. | 2020 |
| Xylitol and its role in pentosuria | Johnson, R. | 2019 |
| Genetic testing for dicarbonyl compounds | Williams, L. | 2018 |
Catalog of Genes and Diseases from OMIM
The Catalog of Genes and Diseases from OMIM is a comprehensive resource that provides information on genes, genetic variants, and related diseases. It serves as a centralized repository for essential information related to genes and diseases, making it a valuable tool for researchers and healthcare professionals.
The catalog includes a wide range of genes and diseases, covering various biological processes and conditions. It lists genes involved in processes such as protein synthesis, cellular signaling, and metabolic pathways. By exploring the catalog, researchers can gain insights into the genetic basis of diseases and understand the underlying mechanisms.
One gene listed in the catalog is the DCXR gene. This gene encodes the enzyme xylitol dehydrogenase, which plays a role in the metabolism of xylitol, a naturally occurring compound. Changes in the DCXR gene can lead to conditions such as dicarbonyl stress and pentosuria.
The catalog provides additional resources for each gene and disease entry. These resources include links to other databases, scientific articles, and references on PubMed. Researchers can use these resources to access further information and stay up-to-date with the latest research in the field.
The catalog also includes information on the localization and expression of genes and proteins. This information is crucial for understanding how genes and proteins function within cells and tissues. It can help researchers identify potential targets for drug development and design targeted therapies.
Healthcare professionals can also benefit from the catalog by accessing information on genetic testing for specific diseases. The catalog provides information on available tests, testing laboratories, and associated clinical guidelines. This information can aid in the diagnosis and management of genetic conditions.
In summary, the Catalog of Genes and Diseases from OMIM is a valuable resource that provides a comprehensive overview of genes, genetic variants, and related diseases. Its extensive coverage, along with additional resources and databases, make it an essential tool for researchers, healthcare professionals, and anyone interested in understanding the genetic basis of diseases.
Gene and Variant Databases
Gene and Variant databases are essential resources for storing and organizing information about genes, genetic conditions, and variants. These databases play a crucial role in the field of genetics, providing a centralized location for researchers and clinicians to access comprehensive and up-to-date information.
One of the most popular gene databases is the Online Mendelian Inheritance in Man (OMIM), which catalogues genes and genetic conditions. OMIM provides detailed information on genes, including their names, localization, functions, and associated diseases. It also includes references to scientific articles and other resources.
In addition to OMIM, there are several other databases that focus on specific genes or diseases. For example, the Di Carbonyl Xylulose Reductase (DCXR) gene, which is involved in the production of pentosuria and related kidney diseases, has its own database. This database lists the changes and variants found in the DCXR gene, as well as the associated health conditions.
Testing the DCXR gene and its variants is crucial for diagnosing and managing related diseases. Gene testing can identify changes in the DCXR gene that may affect its function and lead to health problems. These tests can be performed using various methods, such as DNA sequencing and protein localization.
Gene and variant databases provide a comprehensive list of genetic changes and their associated conditions. By referencing these databases, researchers and clinicians can identify the specific variants and conditions related to the DCXR gene. This information can be used to develop targeted treatments and interventions.
Examples of Gene and Variant Databases:
- Online Mendelian Inheritance in Man (OMIM)
- GeneTests
- Human Gene Mutation Database (HGMD)
- PubMed
- dbSNP
These databases contain a wealth of information on genes, variants, and associated conditions. They serve as valuable resources for researchers, clinicians, and individuals interested in genetic processes and diseases.
References
- Conditions for testing additional genes are listed in OMIM and PubMed.
- Dicarbonyl compounds found during the reaction of xylitol with pentosuria variant sperm.
- Genetic changes in the DCXR gene can result in pentosuria.
- The DCXR gene encodes for the protein dicarbonyl/L-xylulose reductase.
- Genetic information and related diseases can be found in databases such as OMIM and PubMed.
- The localization of DCXR protein is mainly in the kidney.
- Scientific articles on DCXR gene are available in resources like PubMed.
- Genes essential for various processes and health conditions are cataloged in databases like OMIM.