Dasiglucagon Injection

Dasiglucagon injection is used along with emergency medical treatment to treat severe hypoglycemia (very low blood sugar) in adults and children 6 years of age and older with diabetes. Dasiglucagon injection is in a class of medications called glucagon receptor agonists. It works by causing the liver to release stored sugar to the blood.

🔔 How should this medicine be used?

Dasiglucagon injection comes as a solution (liquid) in a prefilled syringe and an auto-injector device to inject subcutaneously (just under the skin). It is usually injected as needed at the first sign of severe hypoglycemia. After the injection, the patient should be turned onto their side to prevent choking if they vomit. Use dasiglucagon injection exactly as directed; do not inject it more often or inject more or less of it than prescribed by your doctor.

Ask your doctor or pharmacist to show you, family, or caregivers who could be injecting the medication how to use and prepare dasiglucagon injection. Before a friend or family member uses dasiglucagon injection for the first time, read the patient information that comes with it. This information includes directions for how to use the injection device. Be sure to ask your pharmacist or doctor if you or your caregivers have any questions about how to inject this medication.

Following a dasiglucagon injection, an unconscious person with hypoglycemia (low blood sugar) will usually wake within 15 minutes. Once the dasiglucagon has been given, immediately contact a doctor and get emergency medical treatment. If the person does not awaken within 15 minutes after an injection, give one more dose of dasiglucagon. Feed the individual a fast-acting source of sugar (e.g., regular soft drink or fruit juice) and then a long-acting source of sugar (e.g., crackers, cheese or a meat sandwich) as soon as they awaken and are able to swallow.

Always look at the dasiglucagon solution before it is injected. It should be clear, colorless, and free of particles. Do not use dasiglucagon injection if it is cloudy, contains particles, or if the expiration date has passed. Ask your doctor or pharmacist how to dispose of the puncture-resistant container.

Dasiglucagon can be injected with the prefilled syringe or autoinjector in the upper arm, thigh, stomach, or buttocks. Roll back any clothing to expose bare skin; do not inject through clothes. Never inject the dasiglucagon prefilled syringe or autoinjector into a vein or muscle.

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It is important that all patients have a household member who knows the symptoms of low blood sugar and how to administer dasiglucagon. If you have low blood sugar often, keep dasiglucagon injection with you at all times. You should and a family member or friend should be able to recognize some of the signs and symptoms of low blood sugar (i.e., shakiness, dizziness or lightheadedness, sweating, confusion, nervousness or irritability, sudden changes in behavior or mood, headache, numbness or tingling around the mouth, weakness, pale skin, sudden hunger, clumsy or jerky movements). Try to eat or drink a food or beverage with sugar in it, such as hard candy or fruit juice, before it is necessary to administer dasiglucagon.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.