CARD9 gene

The CARD9 gene is a central gene in a pathway related to immune response against fungal infections. These infections, caused by Candida yeast and other fungal species, can lead to chronic and severe conditions in affected people. The CARD9 gene, also known by other names listed in scientific resources such as OMIM and PubMed, has been identified as a key player in the recognition of fungal pathogens by the immune system.

Familial candidiasis, a condition inherited from changes in the CARD9 gene, has been documented in several family registries and databases. Additional tests and genetic testing resources have been developed for the identification of variants in the CARD9 gene associated with fungal infections and related diseases. The production of the CARD9 protein, encoded by this gene, plays a crucial role in the immune response against fungus and is essential for preventing infections.

Scientific articles and clinical references provide valuable information about the role of the CARD9 gene in fungal infections and its implications for human health. The CARD9 pathway is part of a complex network of genes and immune processes involved in the defense against fungal pathogens. By understanding the functions of the CARD9 gene and its associated pathway, researchers hope to develop new strategies for the treatment and prevention of fungal infections.

In conclusion, the CARD9 gene is a key player in the immune response against fungal infections. Variants in this gene can lead to familial candidiasis and other related conditions. Through scientific research and genetic testing, the role of the CARD9 gene in recognizing and defending against fungal pathogens is being elucidated, providing important insights into the development of improved treatments and preventive measures.

Health Conditions Related to Genetic Changes

Genetic changes in the CARD9 gene have been identified as the cause for various inherited health conditions. CARD9, also known as caspase recruitment domain family member 9, is a gene involved in the immune system’s response to fungal infections.

One of the main health conditions related to changes in the CARD9 gene is familial candidiasis. This condition is characterized by chronic or recurrent fungal infections caused by Candida yeast. People with familial candidiasis have an increased susceptibility to these infections, and they may experience symptoms such as skin rashes, nail abnormalities, and oral thrush.

Scientific databases and resources like OMIM and PubMed provide valuable information and references on genetic changes and related health conditions. The CARD9 gene and its role in immune response and fungal infections are well-documented in scientific articles and studies.

Health conditions related to CARD9 gene changes can be identified through genetic testing. These tests can detect genetic variants or changes in the CARD9 gene that may contribute to an individual’s susceptibility to fungal infections, such as candidiasis.

The International Registry of CARD9 Deficiency, a central database for gathering information on individuals with CARD9 gene changes, recognizes and catalog the names of families affected by these conditions. It provides resources, support, and clinical information for people and families with CARD9-related health conditions.

In summary, genetic changes in the CARD9 gene can lead to an increased risk of fungal infections, particularly familial candidiasis. Scientific databases and resources, along with genetic testing, can help in identifying these conditions and providing support for affected individuals and families.

Familial candidiasis

Familial candidiasis refers to a genetic condition characterized by chronic and recurrent infections caused by the Candida fungus. It is a rare disease that affects the immune system and leads to an increased susceptibility to Candida infections.

This condition is inherited in a familial manner, meaning that it can be passed down from one generation to another. It is associated with genetic changes or variants in the CARD9 gene, which plays a crucial role in the immune response against fungal infections.

The CARD9 gene is part of a pathway that recognizes and responds to fungal infections. Variants in this gene can result in impaired production of immune molecules, leading to a weakened immune response against Candida. This, in turn, allows the fungus to persist and cause recurrent infections.

Genetic testing can be performed to identify changes or variants in the CARD9 gene. This testing is recommended for individuals with a family history of recurrent Candida infections or other immune conditions. It can provide valuable information for the diagnosis and management of familial candidiasis.

In addition to the CARD9 gene, other genes and genetic factors may also play a role in familial candidiasis. Scientific articles listed in the PubMed database can provide more information on these genes and their association with the condition.

If you suspect that you or a family member may have familial candidiasis, it is important to consult a healthcare professional for proper evaluation and diagnosis. They may recommend genetic testing and other specialized tests to confirm the diagnosis and guide treatment.

Central registries and databases, as well as genetic resources and family health resources, can help connect individuals and families affected by familial candidiasis. These resources provide information, support, and opportunities for collaboration and research.

Other Names for This Gene

  • CARD9 gene
  • Caspase recruitment domain family member 9
  • Candida-associated CARD9
  • Familial Candida infections-associated CARD9
  • Candida interleukin-1 receptor-associated kinase 2
  • CARD9, innate immune signal transducer
  • Caspase recruitment domain-containing protein 9

This gene is also known by several other names, including:

  • CARD9
  • Candida-associated CARD9
  • Familial Candida infections-associated CARD9
  • Candida interleukin-1 receptor-associated kinase 2
  • CARD9, innate immune signal transducer
  • Caspase recruitment domain-containing protein 9
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These different names reflect the various functions and conditions associated with the gene. It has been identified as a key player in the immune response to fungal infections, particularly Candida infections. CARD9 is part of the CARD family of genes, which are involved in the recognition of pathogens and the activation of immune responses.

This gene has been the subject of numerous scientific articles and studies, and its role in various conditions, including chronic fungal infections and genetic diseases, has been well-documented. The CARD9 gene is listed in several genetic databases and resources, including OMIM (Online Mendelian Inheritance in Man) and the GeneTests genetic testing registry.

Additional information about this gene and related genetic conditions can be found in the scientific literature, as well as online resources such as PubMed and the CARD9 gene catalog. These resources provide a wealth of information for researchers, healthcare professionals, and individuals interested in learning more about familial Candida infections and other conditions caused by changes in the CARD9 gene.

Gene Pathway Production From The Immune
CARD9 Central Production Of Interleukin-17 From
CARD9 Pathway Recognizes Fungal Infections On
CARD9 Information From OMIM And Other
CARD9 Databases And References For Additional
CARD9 Family Genetic Testing And Registry

Additional Information Resources

Here are some additional resources for more information on the CARD9 gene and related conditions:

  • OMIM database: OMIM is a comprehensive catalog of genetic diseases and their associated genes. It provides detailed information on the CARD9 gene and its variants.
  • Genetic testing: Genetic testing can be done to identify inherited changes in the CARD9 gene. This can help diagnose familial candidiasis and other genetic conditions related to fungal infections.
  • PubMed: PubMed is a database of scientific articles. You can find research articles on CARD9 gene and related conditions such as chronic candidiasis and immune candidiasis.
  • Registry databases: Registry databases like the Familial Candidiasis Registry can provide information on individuals and families affected by CARD9 gene variants.
  • Health organizations: Various health organizations may have information on the CARD9 gene and related conditions. They can provide resources and support for individuals and families affected by these conditions.
  • Scientific articles: Scientific articles published in journals like Immunology and Clinical Immunology often discuss the role of the CARD9 gene in fungal infections and immune system function.
  • Centralized resource websites: Websites like CARD9.org and Genetic and Rare Diseases Information Center (GARD) provide centralized information on the CARD9 gene and related conditions.

Tests Listed in the Genetic Testing Registry

The Genetic Testing Registry recognizes the following tests for the CARD9 gene. These tests can be used to identify changes in the CARD9 gene that are associated with familial candidiasis, a chronic fungal infection. Familial candidiasis is inherited from family members and is related to changes in the immune pathway for recognizing fungal infections.

The tests listed in the Genetic Testing Registry for the CARD9 gene include:

  • CARD9 Gene Sequencing: This test analyzes the DNA sequence of the CARD9 gene to identify any changes or variants that may be present.
  • CARD9 Gene Deletion/Duplication Analysis: This test looks for deletions or duplications in the CARD9 gene, which can also contribute to familial candidiasis.

These tests are useful for people who have been diagnosed with familial candidiasis or have a family history of the condition. By identifying changes in the CARD9 gene, healthcare professionals can provide more targeted treatment and management strategies for patients.

In addition to the tests listed in the registry, there are other scientific resources available to learn more about the CARD9 gene and its role in familial candidiasis. PubMed, OMIM, and other genetic databases can provide further information on the gene and related conditions.

References to articles and publications related to the CARD9 gene and familial candidiasis can also be found in these databases. These resources can help healthcare professionals stay updated on the latest research and findings in the field.

Overall, the Genetic Testing Registry serves as a central catalog for genetic tests related to various diseases. In the case of the CARD9 gene, tests listed in the registry can aid in the diagnosis and management of familial candidiasis.

Scientific Articles on PubMed

PubMed is a valuable resource for finding information on genetic research and related topics, including the CARD9 gene. This gene plays a crucial role in the immune response to fungal infections, particularly those caused by candida yeast.

Scientific articles in PubMed provide a wealth of information on the CARD9 gene and its involvement in familial diseases and chronic conditions. These articles cover various aspects of the gene, including its function, genetic changes related to diseases, and testing methods.

One of the central findings is that mutations in the CARD9 gene can lead to a higher susceptibility to fungal infections, such as candidiasis. These infections can have severe health implications, particularly for people with inherited or familial conditions.

PubMed offers a catalog of scientific articles that have identified genetic changes in the CARD9 gene. These articles provide insights into the role of the gene in immune responses, specifically in recognizing and responding to fungal infections. The production of specific proteins by the CARD9 gene is crucial for an effective immune response against candida and other fungal pathogens.

See Also:  TGM3 gene

The articles listed in PubMed include information on the variant gene names, testing methods, and clinical manifestations associated with CARD9 gene mutations. They also highlight other genes and pathways that may be related to fungal infections and immune conditions.

For additional information, PubMed can be used in conjunction with resources such as OMIM (Online Mendelian Inheritance in Man) and family genetic databases. These resources provide a comprehensive overview of the genetic and familial aspects of candidiasis and other infectious diseases.

Scientific articles on PubMed are invaluable for advancing our understanding of the CARD9 gene and its implications for human health. They contribute to ongoing research and provide a basis for the development of improved diagnostic tests and treatment strategies.

Clinicians, researchers, and individuals interested in genetic research and fungal infections should explore the articles available on PubMed for a deeper understanding of the CARD9 gene and its significance.

Catalog of Genes and Diseases from OMIM

The catalog of genes and diseases from OMIM is a comprehensive resource for understanding the genetic basis of various health conditions. It provides information on different variants of genes that can cause diseases, including those related to the CARD9 gene.

The CARD9 gene is involved in the immune response to fungal infections. Mutations in this gene can lead to various immune-related disorders, such as familial candidiasis. Familial candidiasis is an inherited condition characterized by chronic infections caused by the yeast Candida. It affects the immune system’s ability to recognize and fight against the fungus.

The catalog lists different genetic changes and variants in the CARD9 gene that have been identified in people with familial candidiasis. It also provides references to scientific articles and databases where additional information about these genetic changes can be found.

The information available in the catalog is essential for genetic testing and counseling. Genetic testing can help in the diagnosis of familial candidiasis and other related conditions. It involves analyzing the DNA sequence of the CARD9 gene to identify any genetic changes or variants that may be present.

By understanding the genetic basis of these diseases, healthcare professionals can better manage and treat affected individuals. The catalog also serves as a valuable resource for researchers, providing insights into the underlying mechanisms and pathways related to the CARD9 gene and fungal infections.

Overall, the catalog of genes and diseases from OMIM is a comprehensive and reliable source of information on genetic conditions, including those related to the CARD9 gene. It provides a centralized repository of knowledge, connecting researchers, healthcare professionals, and individuals interested in understanding the genetic basis of various diseases.

Gene and Variant Databases

There are several gene and variant databases that serve as registries for storing information related to the CARD9 gene and its variants. These databases are central repositories that list and provide information on the different variants of the gene that have been identified. They recognize the importance of these gene variants in human health and their role in the production of diseases.

One such database is the Clinal Gene Variant database, which focuses specifically on genetic variants associated with Candidiasis, a fungal infection. This database catalogs the different variants of the CARD9 gene that have been found in people with familial Candidiasis, chronic yeast infections caused by Candida fungus. It provides detailed information on the genetics of these conditions, including references to related articles from PubMed and OMIM.

Additionally, the ImmunoBase database is a comprehensive resource for genetic information related to the immune system. It contains detailed information on the CARD9 gene, including its role in the immune pathway and its interaction with other genes. This database includes not only information on the CARD9 gene, but also on other genes involved in immune-related conditions and diseases.

Genetic testing for CARD9 gene variants can be done using resources provided by these databases. Clinicians and researchers can use the information stored in these databases to identify specific gene variants and their potential implications for human health. This information can be crucial for diagnosing and treating patients with familial Candidiasis and other immune-related diseases.

The gene and variant databases serve as valuable tools for researchers and clinicians working in the field of genetics and immunology. They provide a centralized repository of information on gene variants, allowing for easy access to information related to the CARD9 gene and its role in immune-related conditions. By cataloging and organizing this information, these databases enable researchers to make new discoveries and advancements in the field.

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