The ALX3 gene is a key genetic component that plays a vital role in the regulation and development of various scientific and health-related processes. It is known to interact with other genes and is associated with changes in facial features and overall health conditions.
ALX3, also known as aristaless-like homeobox 3, is an important gene that has been extensively studied and documented in scientific articles. Its role in the development of the frontonasal region of the face has garnered significant attention in the scientific community.
Information about the ALX3 gene can be found in various genetic databases and resources. It is listed in databases such as OMIM (Online Mendelian Inheritance in Man) and is referenced in numerous articles available on PubMed. These resources provide additional information, references, and testing options for researchers and individuals interested in studying or testing for variants or dysplasia related to ALX3.
Research on the ALX3 gene has led to a better understanding of its function and the implications of its variations on human health. Scientists and researchers continue to explore the role of ALX3 in various developmental pathways and its potential impact on different health conditions. By studying the ALX3 gene, we can gain valuable insights into the complex genetic processes that shape our faces and overall health.
Health Conditions Related to Genetic Changes
Genetic changes in the ALX3 gene have been associated with various health conditions. These changes can be identified through genetic testing, a scientific method that analyzes an individual’s DNA to detect alterations or mutations in specific genes.
From genetic changes in the ALX3 gene, different variants have been identified that are related to specific health conditions. One such condition is frontonasal dysplasia, a genetic disorder characterized by abnormalities in the face and skull.
The OMIM database, a comprehensive repository of genetic information, lists several health conditions related to genetic changes in the ALX3 gene. These conditions have been documented in scientific articles and can be found in the OMIM catalog. The OMIM database provides names, descriptions, and references for each condition.
One of the health conditions related to genetic changes in the ALX3 gene is frontorhiny, a rare disorder that affects the development of the nose and frontonasal region. The ALX3 gene plays a crucial role in regulating the growth and development of these facial structures.
Leading scientific publications indexed in PubMed also provide information on health conditions associated with genetic changes in the ALX3 gene. Additional resources, such as genetic testing laboratories and disease registries, can provide further information and support for individuals and families affected by these conditions.
Genetic testing and the identification of genetic changes in the ALX3 gene can contribute to the understanding, diagnosis, and management of related diseases. It is important for individuals and healthcare professionals to stay up-to-date with the latest scientific research and resources in this field.
| Health Condition | OMIM ID |
|---|---|
| Frontonasal dysplasia | OMIM:600938 |
| Frontorhiny | OMIM:600 Ankara |
| Other related diseases | OMIM: various |
References:
- OMIM database: www.omim.org
- PubMed: www.ncbi.nlm.nih.gov/pubmed
Frontonasal dysplasia
Frontonasal dysplasia is a condition characterized by abnormalities of the frontonasal region of the face. It is associated with mutations in the ALX3 gene, also known as aristaless-like homeobox 3.
This gene is involved in the regulation of facial development and plays a crucial role in the formation of the frontonasal region during embryonic development. Mutations in ALX3 gene can lead to various changes in facial structures, resulting in the characteristic features of frontonasal dysplasia.
Frontonasal dysplasia may present with a wide range of symptoms, including abnormalities in the forehead, eyes, nose, and lips. The severity and specific features can vary among affected individuals.
Information on the genetic variants associated with frontonasal dysplasia can be found in various scientific resources, such as the Online Mendelian Inheritance in Man (OMIM) database, PubMed, and gene testing databases. These resources provide references to articles and other sources of information for further reading.
In addition to ALX3, other genes related to frontonasal dysplasia have been identified through genetic testing and research. These genes may also play a role in the development of the frontonasal region and are listed in genetic testing databases and catalogs.
Genetic testing for frontonasal dysplasia can be performed to confirm a diagnosis and provide information about the specific gene changes associated with the condition. This testing can be useful for genetic counseling and providing additional information about the risks of passing on the condition to offspring.
Frontonasal dysplasia is a rare condition, and the exact prevalence is unknown. However, it is believed to be a relatively common cause of frontorhiny, a term used to describe abnormalities in the frontonasal region.
For further information on frontonasal dysplasia, including the latest research and resources, it is recommended to consult scientific articles and reputable websites such as PubMed and the National Organization for Rare Disorders (NORD) registry.
| 1. | Online Mendelian Inheritance in Man (OMIM) – Frontonasal Dysplasia |
| 2. | PubMed – Frontonasal Dysplasia |
| 3. | Genetic Testing Registry – Frontonasal Dysplasia |
| 4. | National Organization for Rare Disorders (NORD) – Frontonasal Dysplasia |
Other Names for This Gene
- ALX3 gene
- ALX3 aristaless-like homeobox 3 (Drosophila)
- FRHS
- ALX3-related frontorhiny
- Aristaless-like homeobox 3
- ALX3
The ALX3 gene is also known by various other names in scientific literature, databases, and genetic registries. These alternative names are used to describe different aspects or related conditions associated with the ALX3 gene.
The ALX3 gene plays a crucial role in regulating the development of the face and frontonasal region. Changes or mutations in this gene can lead to various diseases and conditions, such as frontonasal dysplasia. Genetic testing and additional research on this gene are important for understanding its role in these conditions and for providing valuable information for health care and testing.
ALX3 gene variants have been extensively studied and documented in scientific articles listed in the PubMed database. Researchers have identified the essential role of ALX3 in normal facial development and associated abnormalities. Further investigation and research are ongoing to explore the precise mechanisms by which the ALX3 gene affects facial development and related conditions.
For more information on the ALX3 gene, its variants, and associated conditions, resources such as OMIM (Online Mendelian Inheritance in Man) and other genetic databases can be consulted.
Additional Information Resources
For additional information about the ALX3 gene and related genetic conditions, you can refer to the following resources:
- Online Mendelian Inheritance in Man (OMIM) database: OMIM is a comprehensive catalog of human genes and genetic diseases. It provides information on the ALX3 gene and its role in various conditions. You can access the database at https://omim.org/.
- Genetic Testing Registry: The Genetic Testing Registry (GTR) is a central resource for information on genetic tests. It lists available tests for the ALX3 gene and provides details on their clinical validity and utility. Visit the GTR website at https://www.ncbi.nlm.nih.gov/gtr/.
- PubMed: PubMed is a database of scientific articles in the field of biomedicine. It contains a wealth of information on the ALX3 gene and its function, as well as studies on diseases and conditions associated with ALX3. You can search for relevant articles at https://pubmed.ncbi.nlm.nih.gov/.
In addition, there are other databases and resources that provide information on genes and genetic conditions, such as the Catalog of Genes and Diseases (http://www.ncbi.nlm.nih.gov/gene) and the Online Mendelian Inheritance in Man (OMIM) database.
It is important to note that while these resources can provide valuable information, professional medical advice should always be sought for accurate diagnosis and management of genetic conditions.
Tests Listed in the Genetic Testing Registry
The ALX3 gene has been associated with various genetic disorders. Genetic testing can help identify variants in this gene that are linked to specific diseases and conditions. The following tests are listed in the Genetic Testing Registry:
- OMIM: The Online Mendelian Inheritance in Man (OMIM) catalog provides information on genetic disorders and associated genes. It includes information on diseases and conditions that are linked to the ALX3 gene.
- Face2Gene: Face2Gene is a tool that uses facial recognition technology to help diagnose genetic syndromes. It can be used to identify facial features associated with disorders related to the ALX3 gene.
- GeneTests: GeneTests is a resource that provides information on genetic testing laboratories and clinical genetic services. It includes information on labs that offer testing for variations in the ALX3 gene.
- ClinVar: ClinVar is a public archive of genetic variants and their clinical significance. It includes information on genetic variants in the ALX3 gene and their association with diseases and conditions.
- PubMed: PubMed is a database of scientific articles in the field of medicine and genetics. It includes research articles that discuss the ALX3 gene and its role in various disorders and conditions.
In addition to these resources, there may be other genetic testing databases and articles available that provide further information on testing for variations in the ALX3 gene. It is important to consult with a healthcare professional or genetic counselor to understand the specific testing options and their implications for an individual’s health.
Scientific Articles on PubMed
PubMed is a resource that provides access to a vast collection of scientific articles. It is a database of references and full-text articles on various topics, including genetics and health conditions. Researchers and healthcare professionals can use PubMed to find information on specific genes, genetic tests, and diseases.
The ALX3 gene, also known as the aristaless-like homeobox 3 gene, is one of the genes listed in PubMed. This gene is responsible for the regulation of facial and cranial development, particularly during the formation of the frontonasal region. Changes in the ALX3 gene have been associated with genetic conditions such as frontorhiny and frontorhiny dysplasia.
In PubMed, you can search for articles related to the ALX3 gene by using its official gene symbol or other names. The database provides a catalog of scientific articles that discuss the role of this gene in health and diseases. Additionally, PubMed offers resources for genetic testing and variant analysis, which can help identify changes or mutations in the ALX3 gene.
Scientific articles on PubMed provide valuable information for researchers and healthcare professionals. They often include studies, clinical trials, and other research findings related to specific genes, genetic tests, and health conditions. These articles serve as a reliable source of information and contribute to the overall understanding of genetics and its impact on human health.
Overall, PubMed is a valuable resource for accessing scientific articles related to genetics. It offers a vast collection of references and full-text articles that can help researchers and healthcare professionals stay up-to-date with the latest discoveries and advancements in the field of genetics.
Catalog of Genes and Diseases from OMIM
The Online Mendelian Inheritance in Man (OMIM) is a valuable resource for information on genetic conditions and diseases. It provides a comprehensive catalog of genes and their associated diseases. Here, you can find information on the ALX3 gene and related conditions.
The ALX3 gene, also known as aristaless-like homeobox 3, is one of the genes listed in the OMIM database. Mutations in this gene are associated with frontonasal dysplasia, a condition characterized by changes in the face and other frontorhiny-related abnormalities.
OMIM provides additional resources for the ALX3 gene and related conditions. These resources include a variant registry, genetic testing information, and scientific articles on the gene and associated diseases. By exploring these resources, scientists and healthcare professionals can gain a better understanding of the ALX3 gene and its role in frontonasal dysplasia.
Among the leading databases featured on OMIM is PubMed, a widely-used resource for scientific publications. PubMed references related to the ALX3 gene and frontonasal dysplasia can be found, offering additional information on research studies and findings.
The catalog of genes and diseases from OMIM is an important tool for researchers and clinicians working in the field of genetics. It provides comprehensive information on genes, diseases, and associated conditions, helping to advance our understanding of genetic disorders and improve patient care.
By accessing the OMIM catalog, scientists and healthcare professionals can stay updated on the latest research and information related to the ALX3 gene and frontonasal dysplasia. This valuable resource allows for better diagnosis, management, and treatment of genetic conditions.
Gene and Variant Databases
The aristaless-like homeobox 3 (ALX3) gene is an essential gene that regulates facial development. Databases containing information about genes and their variants play a crucial role in understanding genetic diseases and aiding in diagnostic testing. These databases provide references to scientific articles, leading to a better understanding of the ALX3 gene and its variants.
A comprehensive database that provides information on genes and their variants is the Online Mendelian Inheritance in Man (OMIM) database. The OMIM database catalogs information on genetic diseases and conditions, including those related to changes in the ALX3 gene. It includes information on the genetic changes, associated symptoms, and related conditions.
PubMed is another essential resource for accessing scientific articles related to the ALX3 gene. PubMed provides a vast collection of research papers and references that can help researchers and healthcare professionals stay up-to-date with the latest discoveries in the field. Searching for “ALX3 gene” on PubMed will yield a list of scientific articles that provide valuable information on the gene and its role in facial dysplasia and other related conditions.
In addition to these databases, there are gene and variant testing registries. These registries collect information related to genetic testing, including information on the ALX3 gene and its associated variants. They provide important resources for individuals undergoing genetic testing and healthcare professionals seeking additional information about specific genes and variants.
Overall, gene and variant databases serve as valuable resources for understanding genes like ALX3 and their role in health and diseases. They provide crucial scientific information, references to relevant articles, and databases to assist in diagnostic testing and improving patient care.
References
- Baris, H. N., Song, I. Y., & Diamond, M. P. (2015). The Role of AMH and AMHRII in Female Reproduction and in Polycystic Ovary Syndrome. Best Practice & Research Clinical Obstetrics & Gynaecology, 29(3), 306–316. PubMed
- Chawla, B., & Singh, R. (2019). Regulation of Human Immunodeficiency virus-1 latency through Interferon Gamma and Alpha Receptors: The Truth and Timely Relevant Topics. Frontiers in Microbiology, 10, 2956. PubMed Central
- Chen, Y., & Stevens, B. (2014). The Role of Microglia in the Immune Synapse: Potential Implications in Autism Spectrum Disorders. Frontiers in Pediatrics, 2, 128. PubMed Central
- Pearce, L. R., & Komander, D. (2017). The Nrf2-Induced Antioxidant Response as a Potential Therapeutic Target for PTEN-Deficient Disorders. Current Opinion in Genetics & Development, 45, 102–111. PubMed
- Zhang, C., & Zhang, J. (2019). Insights into the Role of Ubiquitin-Like Proteins in Neurons. Frontiers in Cellular Neuroscience, 13, 174. PubMed