Aflibercept Injection

Aflibercept injection is used to treat wet age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities). It is also used to treat macular edema after retinal vein occlusion (an eye disease caused by blockage of blood flow from the eye that leads to blurry vision and vision loss), diabetic macular edema (an eye disease caused by diabetes that can lead to vision loss), and diabetic retinopathy (damage to the eyes caused by diabetes). Aflibercept injection is also used to treat retinopathy of prematurity (ROP; an eye disease that occurs in premature infants that can lead to vision loss and blindness). Aflibercept injection is in a class of medications called vascular endothelial growth factor-A (VEGF-A) and placental growth factor (PlGF) antagonists. It works by stopping abnormal blood vessel growth and leakage in the eye(s) that may cause vision loss in people with certain eye conditions.

🔔 How should this medicine be used?

Aflibercept injection comes as a solution (liquid) to be injected into the eye by a doctor. It is usually given in a doctor’s office or healthcare facility. Your doctor will give you injections on a schedule that is best for you and your condition.

Before you receive an aflibercept injection, your doctor will clean your eye to prevent infection and numb your eye to reduce discomfort during the injection. After your injection, your doctor will need to examine your eyes before you leave the office.

Aflibercept injection controls certain eye conditions, but does not cure them. Your doctor will watch you carefully to see how well aflibercept injection works for you. Talk to your doctor about how long you should continue treatment with aflibercept injection.