Dexmedetomidine Sublingual and Buccal
Dexmedetomidine is used to treat episodes of agitation in people who have schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) or bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of severe mania, and other abnormal moods). Dexmedetomidine is in a class of medications called alpha2 receptor agonists. It works by changing the activity of certain natural substances in the brain.
🔔 How should this medicine be used?
Dexmedetomidine comes as a sublingual film to place under the tongue or on the lower gum in your mouth (behind the lower lip). It is usually taken as needed as a single dose under the supervision of a healthcare professional. If you are still agitated after you receive your first dose, you may be given up to 2 more additional doses, given at least 2 hours apart.
To take dexmedetomidine sublingual film, remove the film from the foil pouch with clean dry hands and place the film under your tongue. Alternatively, you can place the film on the lower gum (behind the lower lip). The film will stick in place. Close your mouth and leave the film in place until it dissolves completely. Do not chew or swallow the sublingual film. It may take about 6–8 minutes for the film to dissolve under your tongue or about 18 minutes for the film to dissolve on the lower gum.
Do not eat or drink for at least 15 minutes after the film is placed under your tongue. Do not eat or drink for at least 1 hour after the film is placed on your lower gum (behind your lower lip).
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
