Lanadelumab-flyo injection
Lanadelumab-flyo injection is used to prevent swelling and painful attacks of hereditary angioedema (HAE; an inherited condition that causes episodes of swelling in the hands, feet, face, airway, or intestines) in adults and children 2 years of age or older. Lanadelumab-flyo is in a class of medications called monoclonal antibodies. It works by blocking the action of a certain natural substance in the body that causes swelling and pain associated with HAE.
🔔 How should this medicine be used?
Lanadelumab-flyo comes as a solution (liquid) to be injected subcutaneously (under the skin). Initially, when lanadelumab-flyo injection is used in adults and children 6 years of age or older, it is usually given once every 2 weeks. After 6 months, it may be given every 4 weeks depending on how you respond to the medication. When lanadelumab-flyo injection is used in children 2 to 6 years of age, it is usually given once every 4 weeks. Your doctor will decide how often you are to use lanadelumab-flyo based on your body’s response to this medication. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use lanadelumab-flyo exactly as directed. Do not use more or less of it or take it more often than prescribed by your doctor.
Your doctor may decide that you or your caregiver can perform the injections at home. Your doctor will show you or the person who will be injecting the medication how to inject it. You or the person who will be injecting the medication should also read the written instructions for use that come with the medication. Be sure to ask your doctor or pharmacist if you have any questions about how to inject the medication.
Lanadelumab-flyo injection comes in single-use prefilled syringes and vials. Allow the syringe and vial to warm to room temperature for 15 minutes away from direct sunlight before you inject the medication. Do not try to warm the medication by heating it in a microwave, placing it in hot water, or through any other method. Use each syringe, needle, or vial only once and inject all the solution in the syringe or vial. Dispose of used syringes, needles, and vials in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.
Always look at lanadelumab-flyo solution before injecting it. Check that the expiration date has not passed and that the liquid is clear to almost clear and colorless to slightly yellow and does not contain visible particles. Do not use lanadelumab-flyo injection if it is expired or if the liquid is cloudy or contains particles. Do not shake it.
You can inject lanadelumab-flyo anywhere on the front of your thighs (upper leg) or abdomen (stomach) except your navel and the area 2 inches (5 centimeters) around it. If a caregiver injects the medication, the back of the upper arm may also be used. To reduce the chances of soreness or redness, use a different site for each injection. Do not inject into an area where the skin is tender, bruised, red, or hard or where you have scars or stretch marks. Give each injection at least 1 inch (2.5 centimeters) away from a spot that you have already used and at least 2 inches (5 centimeters) away from any scars.
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Lanadelumab-flyo injection may help control your condition, but does not cure it. Continue to use lanadelumab-flyo injection even if you feel well. Do not stop using lanadelumab-flyo injection without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
