Elotuzumab Injection

Elotuzumab injection is used along with lenalidomide (Revlimid) and dexamethasone or along with pomalidomide (Pomalyst) and dexamethasone to treat multiple myeloma (a type of cancer of the bone marrow) that has not improved with treatment or that had improved after treatment with other medications but later returned. Elotuzumab injection is in a class of medications called monoclonal antibodies. It works by helping the body to slow or stop the growth of cancer cells.

🔔 How should this medicine be used?

Elotuzumab comes as a powder to be mixed with sterile water and given intravenously (into a vein) by a doctor or nurse in a healthcare setting. When used in combination with lenalidomide and dexamethasone it is usually given once every week for the first 2 cycles (each cycle is a 28 day treatment period) and then once every 2 weeks. When used in combination with pomalidomide and dexamethasone it is usually given once a week for the first 2 cycles (each cycle is a 28 day treatment period) and then once every 4 weeks.

A doctor or nurse will watch you closely while you are receiving the infusion and after the infusion to be sure you are not having a serious reaction to the medication. You will be given other medications to help prevent reactions to elotuzumab. Tell your doctor or nurse immediately if you experience any of the following symptoms that may occur during the infusion or for up to 24 hours after you receive the infusion: fever, chills, rash, dizziness, lightheadedness, slowed heart beat, chest pain, difficulty breathing, or shortness of breath.

Your doctor may decrease your dose of elotuzumab or permanently or temporarily stop your treatment. This depends on how well the medication works for you and the side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with elotuzumab.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.