Telbivudine

Telbivudine is no longer available in the U.S.. If you are currently using telbivudine, you should call your doctor to discuss switching to another treatment.

Telbivudine can cause serious or life-threatening damage to the liver and a condition called lactic acidosis (a build-up of an acid in the blood). Tell your doctor if you drink or have ever drunk large amounts of alcohol, if you use or have ever used injectable street drugs, and if you have or have ever had cirrhosis (scarring) of the liver or any liver disease other than hepatitis B. Tell your doctor and pharmacist if you are taking or have taken the following medications: acetaminophen (Tylenol, others); cholesterol-lowering medications (statins); iron products; isoniazid (INH, Nydrazid); medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS); methotrexate (Rheumatrex); niacin (nicotinic acid); or rifampin (Rifadin, Rimactane). If you experience any of the following symptoms, call your doctor immediately: yellowing of the skin or eyes; dark-colored urine; light-colored bowel movements; difficulty breathing; stomach pain; or swelling; nausea; vomiting; unusual muscle pain; loss of appetite for at least several days; lack of energy; extreme weakness or tiredness; feeling cold, especially in the arms or legs; dizziness or lightheadedness; or fast or irregular heartbeat.

Do not stop taking telbivudine without talking to your doctor. When you stop taking telbivudine your hepatitis may get worse. This is most likely to happen during the first several months after you stop taking telbivudine. Be careful not to miss doses or run out of telbivudine. Refill your prescription at least 5 days before you expect that you will need the new supply of medication. If you experience any of the following symptoms after you stop taking telbivudine, call your doctor immediately: extreme tiredness, weakness, nausea, vomiting, loss of appetite, yellowing of the skin or eyes, dark-colored urine, or light-colored bowel movements.

Keep all appointments with your doctor and the laboratory before, during, and after your treatment with telbivudine. Your doctor will order certain tests to check your body’s response to telbivudine during this time.

Talk to your doctor about the risks of taking telbivudine.

🔔 Why is this medication prescribed?

Telbivudine is used for chronic (long term) hepatitis B infection (swelling of the liver caused by a virus) in people who may also show signs of liver damage. Telbivudine is in a class of medications called nucleoside analogues. It works by decreasing the amount of hepatitis B virus (HBV) in the body. Telbivudine does not cure hepatitis B and may not prevent complications of chronic hepatitis B, such as cirrhosis of the liver or liver cancer. Telbivudine does not prevent the spread of hepatitis B to other people through sexual contact, sharing needles, or contact with blood.

Americans see their primary care doctors less often than they did a decade ago. Adults under 65 made nearly 25% fewer visits to primary care providers in 2016 than they did in 2018, according to National Public Radio. In the same time period, the number of adults who went at least a year without visiting a primary care provider increased from 38% to 46%.

🔔 How should this medicine be used?

Telbivudine comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take telbivudine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take telbivudine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

🔔 Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

🔔 What special precautions should I follow?

Before taking telbivudine,

• tell your doctor and pharmacist if you are allergic to telbivudine or any other medications.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: chloroquine (Aralen);erythromycin (E.E.S., E-Mycin, Erythrocin); fenofibrate (Antara, Lofibra, Triglide); gemfibrozil (Lopid); hydroxychloroquine (Plaquenil); medications to prevent rejection of a transplanted organ, such as cyclosporine (Neoral, Sandimmune) or tacrolimus (Prograf); medications to treat fungal infections such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), or voriconazole (Vfend); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone; (Deltasone), penicillamine (Cuprimine); probenecid; or zidovudine (AZT, Retrovir, in Combivir, in Trizivir). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• Tell your doctor if you have or have ever had a liver transplant (surgery to replace a diseased liver), or kidney disease.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking telbivudine, call your doctor. Do not breastfeed while you are taking telbivudine.
• If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking telbivudine.

🔔 What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.