Brompheniramine-Dextromethorphan-Pseudoephedrine, Oral Syrup
Brompheniramine, one of the ingredients in this drug, may cause drowsiness. Taking this medication with other drugs that cause drowsiness raises your risk of drowsiness. You shouldn’t drive, use machinery, or do other activities that require alertness if you need to take this drug with certain drugs used to help you sleep.
Bromphen PSE DM: Ingredients, Uses, Dosage, Side Effects, COVID-19
Bromphen PSE DM is a combination medication used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses. It generally helps relieve cough, runny nose, itchy eyes, and other symptoms.
Bromphen PSE DM contains the following active ingredients:
| Active ingredients (in each 5 mL) |
Purpose |
| Brompheniramine Maleate | Antihistamine |
| Pseudoephedrine HCl | Nasal Decongestant |
| Dextromethorphan HBr | Cough Suppressant |
| *Some products may contain additional ingredients |
Brompheniramine relieves red, irritated, itchy, watery eyes; sneezing; and runny nose caused by allergies, hay fever, and the common cold. Brompheniramine helps control symptoms but does not treat the cause of the symptoms or speed recovery. Brompheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
Pseudoephedrine is used to relieve nasal congestion caused by colds, allergies, and hay fever. It is also used to temporarily relieve sinus congestion and pressure. Pseudoephedrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Pseudoephedrine is in a class of medications called nasal decongestants. It works by causing narrowing of the blood vessels in the nasal passages.
Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions. Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.
Bromphen PSE DM is available in the following doses:
- Bromphen PSE DM Bottle 118ML of 30-2-10MG/5ML
- Bromphen PSE DM Bottle 473ML of 30-2-10MG/5ML
- Bromphen PSE DM Cup 5ML of 30-2-10MG/5ML
Is Bromphen PSE DM a controlled substance?
Although widely abused, Bromphen PSE DM is not a controlled substance under The Controlled Substances Act (CSA). However, it is only available on prescription because it contains pseudoephedrine, a sought-after ingredient for the illicit manufacture of methamphetamine which is a schedule 2 controlled substance.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
• blood vessel disease
• difficulty passing urine
• high blood pressure
• other chronic disease
• taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in the last 14 days
• an unusual or allergic reaction to brompheniramine, dextromethorphan, pseudoephedrine, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
How should I take Bromphen PSE DM?
Follow the directions on the prescription label. Use a specially marked spoon or container to measure your medicine. Household spoons are not accurate. Take this medicine with food or milk if it upsets your stomach. Take your doses at regular times. Do not take more medicine than directed.
| Adults and children 12 years of age and older | 2 teaspoonsful |
| Children 6 to under 12 years of age | 1 teaspoonful |
| Children 4 to under 6 years of age | 1/2 teaspoonful |
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.
Patients over 60 years old may have a stronger reaction to this medicine and need smaller doses.
What happens if I miss a dose?
This medicine is used when needed. If you are on a dosing schedule, skip any missed doses. Do not use two doses at one time. Do not take more than 6 doses in 24 hours.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include feeling depressed or restless, fast or irregular heartbeats, severe drowsiness, loss of coordination, or seizure.
What are the side effects of Bromphen PSE DM?
Common side effects of Bromphen PSE DM include:
• loss of appetite
Bromphen PSE DM can cause serious side effects, if you experience any of the following, report to your doctor or health care professional as soon as possible:
• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• changes in vision
• fast or irregular heartbeat
• feeling faint or lightheaded, falls
• high blood pressure
• trouble passing urine or change in the amount of urine
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I avoid while taking Bromphen PSE DM?
- Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.
- Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
- Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heatstroke.
- This medicine might contain phenylalanine (aspartame). This is only a concern if you have a disorder called phenylketonuria (a problem with amino acids). Talk to your doctor before using this medicine.
- If your symptoms do not improve within 7 days or if they get worse, call your doctor. If you have a severe sore throat, fever, or thick yellow or green mucus, call your doctor.
- Some brands of this medicine may contain alcohol. Read the label carefully or ask your pharmacist so you know what is in your product.
- Children may be more sensitive to this medicine than adults, especially if they take too much. Always read the medicine label closely so you give your child the right amount. Ask your pharmacist or doctor if you are not sure how much medicine to give your child.
Can I use Bromphen-PSE DM for COVID?
No current medicine can prevent or cure COVID-19, but some medications may help alleviate symptoms and manage the impact of the virus. Studies have shown that Bromphen-PSE DM, helps thin and loosen mucus, making it easier to expel from the lungs. Bromphen-PSE DM can also inhibit the body’s cough reflex and help treat a persistent dry cough.
Brompheniramine-Dextromethorphan-Pseudoephedrine, Oral Syrup
Brompheniramine-dextromethorphan-pseudoephedrine oral syrup is a prescription drug that’s available as the brand-name drug Bromfed DM. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.
Brompheniramine-dextromethorphan-pseudoephedrine only comes as a syrup you take by mouth.
This drug is a combination of three drugs in a single form. It contains brompheniramine, pseudoephedrine, and dextromethorphan. It’s important to know about all the drugs in the combination because each drug may affect you in a different way.
Why it’s used
This drug is used to treat upper respiratory symptoms due to allergies or the common cold. These include nasal congestion and cough.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
How it works
Each of the three drugs in this medication belongs to a different class of drugs:
- Brompheniramine belongs to a class called antihistamines.
- Pseudoephedrine belongs to a class called vasoconstrictors.
- Dextromethorphan belongs to a class called antitussives.
A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Brompheniramine and pseudoephedrine work by tightening the blood vessels in your nose. This causes less mucus production and dries out your nose. Dextromethorphan works to decrease your body’s cough reflex. These drugs work together to help relieve your cold or allergy symptoms.
Brompheniramine-dextromethorphan-pseudoephedrine oral syrup can cause several kinds of side effects, including drowsiness. You shouldn’t drive, use machinery, or do other activities that require alertness until you know how this drug affects you.
More common side effects
Some of the more common side effects that can occur with use of this drug include:
- drowsiness
- dry mouth, nose, and throat
- thick lung mucus
- dizziness
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Abnormal heart beat. Symptoms can include:
- fast heart rate
- palpitations (feeling like your heart is skipping a beat)
- dizziness
- fainting
- unexplained bruising
- increased nosebleeds or bleeding from your gums
- weakness
- frequent infections
- an infection that won’t go away
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Brompheniramine-dextromethorphan-pseudoephedrine oral syrup can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with brompheniramine-dextromethorphan-pseudoephedrine are listed below.
Monoamine oxidase inhibitors (MAOIs)
Taking dextromethorphan, one of the ingredients in this drug, with medications called monoamine oxidase inhibitors (MAOIs) can cause fever and low blood pressure. Taking them together may even be fatal (cause death). MAOIs can also increase the effects of brompheniramine and dextromethorphan, the two other drugs in this combination. You should not take brompheniramine-dextromethorphan-pseudoephedrine while taking an MAOI.
Examples of MAOIs include:
- tranylcypromine
- phenelzine
- isocarboxazid
- selegiline
- rasagiline
Anxiety drugs
Brompheniramine, one of the ingredients in this drug, may cause drowsiness. Taking this medication with other drugs that cause drowsiness raises your risk of drowsiness. You shouldn’t drive, use machinery, or do other activities that require alertness if you need to take this drug with certain anxiety drugs.
Examples of these drugs include:
- lorazepam
- clonazepam
- diazepam
- alprazolam
Insomnia drugs
Brompheniramine, one of the ingredients in this drug, may cause drowsiness. Taking this medication with other drugs that cause drowsiness raises your risk of drowsiness. You shouldn’t drive, use machinery, or do other activities that require alertness if you need to take this drug with certain drugs used to help you sleep.
Examples of these drugs include:
- temazepam
- estazolam
- triazolam
- zolpidem
- eszopiclone
- zaleplon
Blood pressure drugs
Pseudoephedrine, one of the ingredients in this drug, may reduce the effectiveness of blood pressure drugs. This may increase your blood pressure. Examples of these blood pressure drugs include:
- terazosin
- doxazosin
- metoprolol
- carvedilol
- atenolol
- propranolol
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
This drug comes with several warnings.
Allergies
This drug can cause a severe allergic reaction. Symptoms can include:
- shortness of breath
- breathing problems
- swelling of your lips and tongue
- itching
- hives
If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Alcohol interaction
The use of drinks that contain alcohol can increase your risk of drowsiness from Brompheniramine-dextromethorphan-pseudoephedrine. If you drink alcohol, talk to your doctor before taking this drug.
Warnings for people with certain health conditions
For people with asthma: Brompheniramine, one of the ingredients in this drug, can cause the mucus in your lungs to thicken. This can make it harder to breathe. Talk to your doctor about whether this drug is safe for you.
For people with narrow angle glaucoma: Brompheniramine, one of the ingredients in this drug, may increase the pressure in your eye and worsen your glaucoma. Talk to your doctor about whether this drug is safe for you.
For people with stomach or intestinal blockage: Brompheniramine, one of the ingredients in this drug, can slow down the movement of your stomach and intestines. This can make a blockage worse. Talk to your doctor about whether this drug is safe for you.
For people with urinary bladder neck blockage: Brompheniramine, one of the ingredients in this drug, can make urine flow problems worse. Talk to your doctor about whether this drug is safe for you.
For people with diabetes: Pseudoephedrine, one of the ingredients in this drug, can increase your blood sugar. Talk to your doctor about whether this drug is safe for you.
For people with high blood pressure: Pseudoephedrine, one of the ingredients in this drug, can increase blood pressure. You shouldn’t use this drug if you have very high blood pressure. Talk to your doctor about whether this drug is safe for you.
For people with heart disease: You shouldn’t use pseudoephedrine, one of the ingredients in this drug, if you have severe heart disease. This drug can increase your blood pressure, heart rate, and the force that your heart uses to beat. This increases your risk of an abnormal heart rhythm, heart attack, stroke, and cardiac arrest. Talk to your doctor about whether this drug is safe for you.
For people with thyroid disease: You shouldn’t use pseudoephedrine, one of the ingredients in this drug, if you have hyperthyroidism (overactive thyroid). This drug can increase your blood pressure, heart rate, and the force that your heart uses to beat. Hyperthyroidism also increases these effects on your heart. Using this drug increases your risk of an abnormal heart rhythm, heart attack, stroke, and cardiac arrest. Talk to your doctor about whether this drug is safe for you.
Warnings for other groups
For pregnant women: This drug is a category C pregnancy drug. That means two things:
- Research in animals has shown adverse effects to the fetus when the mother takes the drug.
- There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.
Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus.
Call your doctor right away if you become pregnant while taking this drug.
For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. This drug should not be used in women who are breastfeeding.
For seniors: Older adults may process this drug more slowly. A normal adult dose may cause levels of the drug to be higher than normal in your body. Your doctor may start you on a lower dose or different dosing schedule.
For children: The safety and effectiveness of this drug in children younger than 6 months of age hasn’t been established.
You shouldn’t use this drug in newborns or premature infants. Overdose of this drug in infants and small children can cause hallucinations (seeing or hearing something that isn’t there) or seizures. Taking too much may even be fatal (cause death). In young children, this drug can cause excitation instead of drowsiness or sedation.