The 8 Best Eye Drops for Allergies of 2023

Price at time of publication: $19

Which Eyedrops Help Eye Allergies?

Allergy eyedrops are liquid medicines used to treat symptoms of eye allergies. Eye allergy symptoms include:

• A burning feeling in your eye
• Feeling like something is in the eye
• Itchy eyes
• Red (bloodshot) eyes
• Swollen eyelid
• Tearing

An eye allergy can be triggered by the same things that cause hay fever, such as:

Certain medications or contact lenses can also be triggers.

Types of Allergy Eyedrops

Your doctor may first suggest you take these steps:

• Use artificial tears.
• Place a cold cloth on the eyes.
• Avoid your allergy triggers.

Which type of allergy eyedrop you use depends on:

Interestingly, Americans show more favor toward Medicare for All healthcare initiatives than they do toward these efforts when they are labeled as “single payer,” most likely due to the popularity of the Medicare program, STAT

• The cause of your allergy
• Your symptoms
• How much the symptoms affect your daily activities

There are many types of allergy eyedrops. Not all treat all allergy symptoms. For example, one that relieves red eyes may not stop the itching.

Some are sold over the counter. For others you need a prescription from a doctor. Some relieve symptoms quickly. Others provide long-term relief.

The types of allergy eyedrops include:

• Antihistamine
• Anti-inflammatory
• Decongestant
• Mast cell stabilizers
• Multiple action

Antihistamine Allergy Eyedrops

Doctors usually recommend these as the first treatment for eye allergies if you can’t get enough relief without drugs.

If you have itchy, watery eyes, antihistamine eyedrops may make you feel better. These medicines block histamine in the body. Histamine is a chemical that your immune system makes when you come in contact with an allergy trigger. It causes many of your allergy symptoms.

Antihistamine eyedrops can quickly ease your symptoms. But relief may only last for a few hours. It can also cause your eyes to be more dry. You may need to use the drops several times a day.

Antihistamine eyedrops include:

• Azelastine hydrochloride (Optivar)
• Emedastine difumarate (Emadine)
• Levocabastine (Livostin)
• Alcaftadine (Lastacaft)

Anti-inflammatory Allergy Eyedrops

These eyedrops fall into two groups:

• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Corticosteroids

NSAID eyedrops affect certain nerve endings. They change the way your body makes you feel itchy.

Ketorolac (Acular, Acuvail) is the only NSAID approved for the treatment of itchy eyes. Itching usually starts to go away about 1 hour after using the eyedrops. These eyedrops often cause stinging or burning when first placed in the eyes.

Corticosteroid eyedrops are used to treat severe, long-term eye allergy symptoms. Prescription steroid eyedrops include loteprednol (Alrex, Lotemax).

Doctors generally don’t recommend corticosteroid drops for long-term use, unless your case is really severe, due to possible side effects such as increased eye pressure and cataracts.

When you use corticosteroid eyedrops, you should have regular checkups with an eye specialist to check on your eye health. These eyedrops can make you more likely to get:

• Cataracts
• Eye infection
• Glaucoma
• Increased pressure in the eye

Decongestant Allergy Eyedrops

These eyedrops can quickly brighten the whites of your eyes and reduce eye redness for a short time. They narrow blood vessels in the eye area. This relieves the red, bloodshot appearance of the eyes but carries longterm risk of “rebound redness,” which is making your eyes permanently bloodshot. As a result, they are not recommended for longterm use.

You can get these eyedrops without a prescription. But doctors don’t recommend them to treat eye allergies.

Examples of over-the-counter decongestant eyedrops are:

• Naphazoline HCL (Clear Eyes)
• Phenylephrine HCL (Refresh)
• Oxymetazoline HCL (Visine)
• Tetrahydrozoline HCL

There are some risks. If you use them for too long, it can make your eye problem worse, with “rebound redness.” Redness and eye swelling can continue even when you stop using the drops.

If you have glaucoma you should never use decongestant eyedrops.

Mast Cell Stabilizer Allergy Eyedrops

These are among the newest types of eyedrops. They help prevent the release of histamine and other chemicals made by your body during an allergic reaction.

Mast cell stabilizers are made to prevent your symptoms.

You may be able to use these drops for many months without any side effects. If you wear contacts, mast cell stabilizers may let you wear them longer.

Over-the-counter mast cell stabilizer drops include:

• Ketotifen fumarate (Claritin Eye, Refresh Eye Itch Relief)

Prescription mast cell stabilizer eyedrops include:

• Cromolyn (Crolom)
• Lodoxamide (Alomide)
• Nedocromil sodium (Alocril)
• Pemirolast potassium (Alamast)

Multiple-Action Allergy Eyedrops

Some eyedrops contain more than one type of medicine. These are called dual-action or multiple-action eyedrops.

Antihistamine/decongestant combination eyedrops reduce eye itching, watery eyes, and redness. Examples include:

• Antazoline phosphate/naphazoline HCL (Vasocon-A)
• Pheniramine maleate/naphazoline HCL (Opcon-A and Naphcon-A)

Antihistamine/mast cell stabilizer combination eyedrops treat and prevent:

These newer eyedrops are especially helpful for people with a condition called allergic conjunctivitis. Examples include:

• Epinastine (Elestat)
• Ketotifen (Alaway, Zaditor)
• Olopatadine hydrochloride (Pataday, Patanol)
• Cetirizine (Zerviate)

Side Effects and Risks

As with any medicine, you should always follow the recommended instructions on the label. You shouldn’t use over-the-counter eyedrops for more than 2 to 3 days. If you use them for longer than that, it can make matters worse.

If you have an eye infection or glaucoma, you shouldn’t use eyedrops. Talk to your doctor about other options.

Some eyedrops may sting or burn when you place them in your eyes. It can help to store them in your fridge.

You can’t use many eyedrops while you wear contact lenses. Your doctor may tell you to remove your lenses before you use the drops and wait at least 10 minutes before you put them back in. Or you may not be able to wear contact lenses at all during treatment with eyedrops.

You’ll need to use most allergy eyedrops several times a day.

Show Sources

Healthy Women: “Ocular Allergies.”

American College of Allergy, Asthma, and Immunology: “Eye Allergy Treatment.”

University of Michigan Kellogg Eye Center: “Allergies of the Eye.”

Kliegman, R.M., Behrman, R.E., Jenson, H.B., Stanton, B.F., editors, Nelson Textbook of Pediatrics,19th edition, Saunders Elsevier, 2011.

Bielory, L. Immunology and Allergy Clinics of North America, February 2008.

The 8 Best Eye Drops for Allergies of 2023

Sarah is a freelance writer with a focus on health and wellness. She has written for publications like Women’s Health, Healthline, and Parents. She taught creative writing for five years, and has a bachelor’s degree in English from Southern Connecticut State University.

Jurairat J. Molina, MD, MBA is a board-certified allergist who has been practicing in field of allergy and clinical immunology for the past two decades.

Pet dander, dust, ragweed, grass, and pollen can trigger your eyes to have an allergic reaction. Common OTC allergy medications may help, but according to Christine Franzese, MD, allergist at the University of Missouri Health Care, eye allergies can be hard to treat. Whether it’s dryness, redness, or itching, eye drops can provide some relief for the different symptoms of eye allergies.

Reviewed & Approved

Bausch + Lomb Alaway Antihistamine Eye Drops is our top pick. It not only provides relief up to 12 hours, but it can be used to treat allergic responses to pollen, pet dander, and grass. We recommend Refresh Optive Lubricant Eye Drops if you wear contacts.

When looking for eye drops, it’s important to choose one with oral antihistamines, as they “will help with eye symptoms about 50% of the time, and nasal steroid sprays, like fluticasone, will help 60% of the time,” she says. We researched dozens of eye drops for allergies and evaluated them for ingredients, price, and treatment duration to find the best eye drops for allergies on the market.

Our Top Picks
Best Overall:
Best Budget:
Best for Redness:
Best for Contact Lens Wearers:
Best for Dry Eyes:
Best for Itchy Eyes:
Best for Sensitive Eyes:
Best for Watery Eyes:
In This Article

Best Overall

Bausch + Lomb Alaway Antihistamine Eye Drops

View On Amazon View On Walmart View On Bed Bath & Beyond

• Broad-spectrum allergy relief
• Lasts up to 12 hours
• Fast acting for irritated eyes

• May sting or burn with application
• Can’t be used while wearing contacts

We chose the Bausch + Lomb Alaway Antihistamine Eye Drops as our top pick because it features 0.025% ketotifen, an opthalmic antihistamine that provides allergy relief. Antihistamines like ketotifen are designed to block the response of histamines. Alaway, with its 12-hour protection, can easily be used to treat common allergic responses to pollen, pet dander, and grass. It starts working right away and can be used with contact lenses (following the directions on the packaging). Eye drops containing only antihistamines, like Alaway, are generally safe for everyday use.

Price at time of publication: $19

Active Ingredients: Ketotifen 0.025% | Dosage: 1 drop in affected eye(s) twice per day or every 8-12 hours

What the Experts Say

“Ketotifen works by reducing eye allergies through its antihistamine and mast cell stabilizer properties. It works within minutes of administering the drops.” —Yuna Rapoport, MD, director of Manhattan Eye in New York City

Best Budget

Visine Allergy Eye Relief Multi-Action Eye Drops

View On Amazon View On Riteaid.com

• Contains an antihistamine for itching and a decongestant for redness
• Can be used up to 4 times a day

• Redness rebound possible
• Doesn’t last as long as other drops

The mere mention of OTC eye drops probably makes you think of Visine. The company has been doing eye care for decades, and they offer several different formulations of drops designed to help with literally any eye problem you could possibly have (yes, even eye strain from too much screen time).

Because Visine products are pretty affordable, their Visine Allergy Eye Relief Multi-Action Eye Drops are a winning budget pick for anyone who needs allergy relief stat without shelling out lots of cash. With both an antihistamine for itching and a decongestant for redness, they’re the eye drops you should grab when allergies catch you by surprise and leave you roaming the pharmacy aisles in desperation.

These eye drops are easy to use, and you can use these drops up to four times per day as needed, but not for more than 72 hours in a row. These drops contain a decongestant which you could become dependent on if you use them consistently. Eye allergies that are seasonal or require longer symptom relief should be treated with a product that doesn’t contain any decongestant.

Price at time of publication: $7

Active Ingredients: Naphazoline HCl 0.025%, Pheniramine maleate 0.3% | Dosage: 1 or 2 drops in the affected eye(s) up to 4 times a day

Best for Redness

Bausch & Lomb Opcon-A Allergy Eye Drops

View On Amazon View On Walmart View On Bed Bath & Beyond

• Relieves itching and redness
• Relief of pollen, grass, and pet dander allergies
• Safe for intermittent use

• May cause redness rebound
• May cause stinging and burning

If eye redness is your biggest problem, you’ll probably have to choose drops that contain a decongestant like naphazoline. This ingredient acts as a vasoconstrictor, meaning it shrinks the inflamed blood vessels so they become less noticeable.

Bausch & Lomb Opcon-A Allergy Eye Drops are a good choice for redness caused by allergies because it also contains an antihistamine. It can do double-duty on your symptoms, reducing redness on the spot while also relieving itching due to grass, pollen, ragweed, and pets.

You need to be careful, though, about overusing this product: Your eyes can become accustomed to the decongestant, and more severe redness can result when you stop using it (which leads you to use the product again, thus continuing the vicious cycle). But intermittent use—up to four times per day for 72 hours at a time—is safe.

Price at time of publication: $10

Active Ingredients: Naphazoline HCI 0.02675%, Pheniramine maleate 0.315% | Dosage: 1 or 2 drops in the affected eye(s) up to 4 times daily

Best for Contact Lens Wearers

Refresh Optive Lubricant Eye Drops

Courtesy of Amazon

View On Amazon View On Riteaid.com

• Lubricates and hydrates dry eyes
• Can be used with contacts
• Relieves grittiness, blurriness, and itching

• Won’t treat allergies
• May need to be applied frequently

Refresh Optive Lubricant Eye Drops mean good news for contact lens wearers who also suffer from allergies: you don’t have to choose between your contacts and freedom from allergy symptoms! Many allergy eye drops are safe to use with soft contacts. The trick, in this case, is keeping your eyes moisturized since the one-two punch of contact lenses and allergy irritation can do a number on your eyes’ overall moisture. Also comes in a preservative-free option.

Price at time of publication: $11

Active Ingredients: Carboxymethylcellulose sodium 0.5%, Glycerin 0.9% | Dosage: 1 or 2 drops in affected eye(s) as needed

Best for Dry Eyes

Systane Lubricant Eye Drops

Courtesy of Amazon

View On Amazon View On CVS

• Like artificial tears for dry, gritty eyes
• Long-lasting moisture for irritated eyes

• Won’t treat allergies
• Not for use with contacts
• No antihistamines

If dryness is your number one eye allergy symptom, you may want to start small with Systane Lubricant Eye Drops, an artificial tear product. You might not need to use antihistamine or decongestant products if lubrication solves your dryness problems.

When it comes to keeping your eyes nice and moist, Systane is a consistently good choice: With two different kinds of glycol, a humectant that attracts and binds water to the outer layer of a surface, these drops can be applied anytime your eyes need a serious refresher.

While these drops work well for lubricating dry eyes caused by allergies, they can also be used to moisturize gritty or blurry eyes, eye strain or fatigue, and excessive tearing. They’re also preservative-free which makes them a great choice for sensitive eyes. They’re basically an all-purpose moisturizer for your eyes.

Price at time of publication: $18

Active Ingredients: Polyethylene glycol 400 0.4%, propylene glycol 0.3% | Dosage: 1 or 2 drops in affected eye(s) as needed

What the Experts Say

“Lubricating drops or artificial tears will treat dry eye, which causes many of the same symptoms that allergic conjunctivitis causes, such as burning, itching, foreign body sensation.” —Yuna Rapoport, MD, director of Manhattan Eye in New York City

Best for Itchy Eyes

ALCON Pataday Once Daily Relief

Courtesy of Amazon
View On Amazon View On CVS View On Riteaid.com

• One application needed per day
• Contains antihistamine ingredient
• Approved for use in kids over 2 years old

• You can’t reapply if it wears off
• May not work as well as ketotifen

If you need an antihistamine for your eye allergies, the last thing you want is one that irritates your eyes even more before it starts working. If you haven’t had success with ketotifen-based eye drops, you may want to try one containing olopatadine, like Alcon Pataday Once Daily Relief. Dr. Franzese says this ingredient typically doesn’t sting as much as some others.

The antihistamine in Alcon Pataday Once Daily Relief targets itchy eyes and other allergic symptoms caused by grass, pollen, ragweed, and animals, like Bausch + Lomb Alaway Antihistamine Eye Drops. It’s perfect for people who work all day around their allergy triggers, since it lasts 16 hours and only needs to be used once a day (although there is also a twice-daily formulation if you need the overnight protection).

Price at time of publication: $9

Active Ingredients: Olopatadine 0.2% | Dosage: 1 drop in affected eye(s) once daily

Best for Sensitive Eyes

Similasan Allergy Eye Relief Drops

Courtesy of Amazon
View On Amazon View On Bed Bath & Beyond View On CVS

• No pharmaceutical ingredients
• Multi-symptom allergy relief
• Gentle so can be used as needed

• May not be strong enough for severe allergies
• Possibility of allergic reaction to natural ingredients

Similasan Allergy Eye Relief Drops are for anyone with sensitive eyes looking for natural eye allergy treatments. Similasan eye drops don’t contain medications, preservatives, or other chemicals, Similasan offers an eye drop containing gentle, non-irritating ingredients. These allergy relief drops treat sensitive eye symptoms such as redness, itching, and stinging.

Because the ingredients are natural, you can use the drops as needed without worrying about side effects or rebound symptoms. They contain three primary botanical extracts that work to tackle your symptoms naturally. The company advises wearers to check with a doctor first before using this product with contact lenses.

Price at time of publication: $7

Active Ingredients: None | Dosage: 2 to 3 drops in affected eye(s) as needed

Best for Watery Eyes

ALCON Zaditor Antihistamine Eye Drops

Courtesy of Amazon
View On Amazon View On Walmart View On Bed Bath & Beyond

• Lasts a long time and works fast
• Original prescription strength
• Broad-spectrum relief for allergens including seasonal

• May sting or burn with application
• Can’t be used while contacts are in eye
• Not a lubricant

Are you sick of hearing about ketotifen yet? Sorry, but we’ve got one more for you. Lots of eye allergy sufferers swear by Alcon Zaditor Antihistamine Eye Drops, which contains this antihistamine powerhouse and relieves your symptoms for 12 hours with just one drop.

If you have watery eyes, you should be looking for a product with an antihistamine—they’re known for their ability to dry up mucus, which is why they are so good at stopping runny noses and post-nasal drip. For watery eyes, an antihistamine can reduce all those excess tears caused by environmental allergens.

Zaditor can help with everything from seasonal pollen to dry air in office buildings, providing both immediate and long-lasting relief. They can be used indefinitely without any rebound effect and are safe for use with contacts, too (per the directions on the packaging).

Price at time of publication: $19

Active Ingredients: Ketotifen 0.025% | Dosage: 1 drop in affected eye(s) twice per day or every 8-12 hours

How We Selected the Best Eye Drops for Allergies

When selecting the best eye drops for allergies, we researched dozens of top brands and formulations. We also spoke to allergists and an ophthalmologist to find out what patients should look for in an over-the-counter solution to eye allergy irritation. When narrowing down our choices, we considered two different types of drops: mast cell stabilizers and antihistamines, as well as the dosages for each product, and whether or not they work for contact lens wearers. Our top priorities were finding eye drops that target allergy-related symptoms and identifying products that are effective without being expensive.

What to Look for in Eye Drops for Allergies

Ingredients

There are two main kinds of ingredients in eye drops that can reduce your allergic reaction to seasonal or environmental triggers:

• Mast cell stabilizers
• Antihistamines

While eye drops that include lubricating ingredients, like the polyethylene glycol found in artificial tears, may be helpful in soothing eye irritation, they don’t actually stop the histamine response at the root of your problems.

The ingredient that will work best varies from person to person, so be ready for a little trial and error.

“If you have tried an antihistamine eye drop and not found relief, you may find relief with a mast cell stabilizer,” says Kathleen Dass, MD, Michigan-based allergist and immunologist. “In rare circumstances, we use both to treat because they work differently.”

You might think that more ingredients equals more kinds of relief, but that’s not necessarily the case. Many eye drops, especially those that reduce redness, include vasoconstrictors in the form of decongestants, and these aren’t safe for long-term use.

“It’s okay to use these drops rarely if you need to—however they will not provide long-term allergy relief [and can also] create rebound redness,” explains Dr. Dass.

Target Symptoms

Because eye drops often focus on relieving a single symptom of allergies, you’ll have to experiment a little when it comes to finding a product that works for you. If you only have one symptom, like dryness, you don’t need a multi-action drop. On the other hand, if your eyes are itchy, red, and watery, that might be your best bet.

As with any other medication, you can’t properly treat your symptoms if you don’t know what they are. Dr. Dass says it’s important to confirm that you’re definitely dealing with eye allergies, not a similar problem like dry eyes or blepharitis (also called granulated eyelids), since those conditions are treated differently. Eye redness and grittiness can also be symptomatic of viral conjunctivitis or pink eye, in which case getting an accurate temperature reading would aid in diagnosis and treatment. You may need to meet with an allergist to hone in on your individual symptoms and, preferably, figure out your triggers; while eye drops can treat symptoms, the only way to prevent symptoms entirely is to avoid your triggers.

Dosage

Most drops will require you to use them once or twice per day. You’ll get the same amount of medication over a 24-hour period, but one way may end up being more preferable to you than the other.

For example, if you find the effects of the drops wearing off after 10 hours but you’re using a once-daily drop, you’ll be left with symptoms for a long time before you can take another dose. But if you wear contact lenses, it could be a total hassle to remove your contacts twice a day for administering drops, warns Dr. Dass. Make sure you think about your schedule and ability to use the drops before choosing between 12- and 24-hour formulations.

Use With Contact Lenses

Speaking of contacts, it’s important to make sure the eye drops are safe for use with your lenses.

“Most eye drop instructions recommend waiting 10 to 15 minutes before putting in your contacts,” says Dr. Dass, who emphasizes the importance of reading the instructions that come with your brand of eye drops (you want the medication to be fully absorbed before you put your lenses in, or they can interfere with the effectiveness of the medication). Also, it is a good idea to take your allergies into account when shopping for contacts to find ones that won’t further exacerbate your symptoms.

Frequently Asked Questions

Can I use allergy eye drops for pink eye?

It depends on what’s causing your pink eye; conjunctivitis can be caused by allergies, a virus, or bacteria, says Yuna Rapoport, MD, director of Manhattan Eye in New York City, so if your pink eye has been caused by allergies then these types of drops would be useful. If a virus or bacteria is the culprit, allergy drops won’t help.
So how do you know if your pink eye is from allergies? Dr. Rapoport says if your symptoms are chronic (i.e., they last over a long period of time, not suddenly), if there is no yellow mucus that comes out, and if the ophthalmologist sees “papillae” or bumps on the inside of the eyelid during an eye exam.

Do eye drops for allergies help with red eye?

Just like with pink eye, the cause for your red eye symptoms matters: if pollen or animal dander (or all that scratching you’re doing because of pollen or pet dander) has made your eyes red and irritated, then allergy eye drops may help.
But Dr. Rapoport stresses that other eye conditions like dry eye, blepharitis, and infection can also cause red eye—and allergy eye drops will not relieve your red eye in those cases.

Can I develop a dependency on eye drops?

If the eye drops contain certain ingredients, you can develop a dependency. The main ingredient to be extremely mindful of is Naphazoline HCI; this is a decongestant ingredient which shrinks the blood vessels in your eye to make them appear less visibly red, but it will cause a rebound effect if used too often.
In other words, the more you use redness relieving eye drops, the redder your eyes will become—and the more you’ll feel like you need to use a redness reliever, kicking off a vicious cycle where you become dependent.
How can you avoid this? By using redness relieving drops with decongestant ingredients sparingly.
“Those drops should not be used more than just every so often for a special occasion or picture,” explains Dr. Rapoport.

How much do allergy eye drops cost?

Because allergy eye drops are generally sold over-the-counter, the price range is largely affordable, with most prices falling under $15. A few of the options on our list are multipacks—great for people who frequently use eye drops or households of allergy-sufferers—which might run closer to $20. The most expensive item on our list is our top choice, Alaway, which comes in a two-pack; our least expensive option is Visine, which came in at under $7 at the time of publication. Name-brand are typically around the same price as generic products.

Why Trust Verywell Health

Sarah Bradley has been writing health content since 2017—everything from product roundups and illness FAQs to nutrition explainers and the dish on diet trends. She knows how important it is to receive trustworthy and expert-approved advice about over-the-counter products that manage everyday health conditions, from GI issues and allergies to chronic headaches and joint pain.