Fibromyalgia

Fibromyalgia is a complex condition that affects many people, especially women. It is characterized by chronic pain, fatigue, and tender points throughout the body. The exact causes of fibromyalgia are still unknown, but researchers believe that a combination of genetic and environmental factors may play a role in its development.

There have been numerous studies and scientific research conducted on fibromyalgia, with many articles published on PubMed and other resources. These studies have helped to shed light on the symptoms, frequency, and overall impact of the disease on patients’ lives.

While physical symptoms such as pain and fatigue are common in fibromyalgia, there are also other associated conditions, such as headaches and temporomandibular joint disorder. Inheritance may also be a factor, as fibromyalgia tends to run in families.

For those seeking more information on fibromyalgia, advocacy groups and support organizations can provide additional resources and support. ClinicalTrials.gov is also a valuable tool for finding ongoing research studies and clinical trials related to fibromyalgia.

Overall, fibromyalgia is a complex condition that affects many people. While the exact causes and mechanisms are still being studied, research has shown that a combination of genetic and environmental factors may play a role in its development. With more scientific research and patient advocacy, we can hope to learn more about fibromyalgia and find effective treatments for those affected by this condition.

Frequency

Fibromyalgia is a chronic condition that affects a significant number of individuals across the globe. The frequency of fibromyalgia varies, but studies suggest that it affects about 2-8% of the population worldwide, with women being more commonly affected than men.

Several factors can contribute to the frequency of fibromyalgia. Scientific studies have shown that genetic inheritance can play a role in the development of the condition, with certain gene variations being more common in fibromyalgia patients. Additionally, environmental factors and lifestyle choices can also contribute to the occurrence of fibromyalgia.

The symptoms of fibromyalgia can vary from one patient to another, with some individuals experiencing more frequent and severe symptoms than others. Common symptoms include widespread pain, fatigue, sleep disturbances, and cognitive difficulties.

Research has also found associations between fibromyalgia and other conditions, such as temporomandibular joint disorder (TMJ), headaches, and irritable bowel syndrome (IBS). These comorbid conditions can further contribute to the frequency of fibromyalgia cases.

In addition to the overall frequency of fibromyalgia, research has also focused on the frequency of specific symptoms within the condition. Studies have shown that the frequency of symptoms like pain and fatigue can vary, with some individuals experiencing these symptoms more frequently and intensely than others.

Understanding the frequency of fibromyalgia and its associated symptoms is crucial for healthcare professionals in guiding treatment and management strategies for patients. It can help tailor interventions to address the specific needs of individual patients, providing better overall care.

Advocacy organizations and support groups play a crucial role in providing information and resources to individuals with fibromyalgia and their families. These organizations often provide additional resources and support, such as educational articles, names of healthcare providers specializing in fibromyalgia, and clinical trial information through websites and other platforms.

Overall, learning more about the frequency of fibromyalgia and associated symptoms contributes to a better understanding of the disease and how it impacts individuals and their families. Scientific research, along with the support from advocacy organizations, can help improve the diagnosis, treatment, and quality of life for those living with fibromyalgia.

References:

1. Clauw DJ. Fibromyalgia and related conditions. Mayo Clin Proc. 2015;90(5):680-692. doi:10.1016/j.mayocp.2015.03.014
2. Walitt B, Fitzcharles MA, Hassett AL, et al. The longitudinal outcome of fibromyalgia: a study of 1555 patients. J Rheumatol. 2011;38(10):2238-2246. doi:10.3899/jrheum.110026
3. Fibromyalgia: Inheritance and genetic risk factors. Mayo Clinic. Accessed December 1, 2021. https://www.mayoclinic.org/diseases-conditions/fibromyalgia/symptoms-causes/syc-20354780
4. ClinicalTrials.gov. Fibromyalgia. Accessed December 1, 2021. https://clinicaltrials.gov/ct2/results?cond=Fibromyalgia
5. PubMed. Fibromyalgia. Accessed December 1, 2021. https://pubmed.ncbi.nlm.nih.gov/?term=fibromyalgia

Causes

The exact cause of fibromyalgia is not known, but researchers believe that it involves a combination of genetic, neurobiological, and environmental factors. Here are some possible causes that have been suggested:

• Genetic factors: Fibromyalgia tends to run in families, suggesting a genetic component. Studies have shown that certain genes may be associated with an increased risk of developing the condition.
• Physical and emotional trauma: Some people with fibromyalgia report experiencing a physical or emotional trauma, such as an infection or a car accident, before the onset of their symptoms. However, not everyone with the condition has experienced such events.
• Abnormal pain processing: People with fibromyalgia may have abnormalities in the way their central nervous system processes pain signals. This could lead to an increased sensitivity to pain and other symptoms associated with fibromyalgia.
• Neurochemical imbalances: Changes in certain neurotransmitters, such as serotonin and dopamine, have been observed in people with fibromyalgia. These neurotransmitters play a role in regulating pain, mood, and sleep, which are all affected in fibromyalgia.
• Other health conditions: Fibromyalgia can be associated with other chronic pain conditions, such as temporomandibular joint disorder, irritable bowel syndrome, and chronic headaches.
• Environmental factors: Some studies have suggested that exposure to certain environmental factors, such as infections or traumatic events, may trigger the development of fibromyalgia in susceptible individuals. However, more research is needed to understand the exact role of these factors.

It is important to note that fibromyalgia is a complex condition with a wide range of symptoms and potential causes. The exact factors that contribute to the development of fibromyalgia may vary from person to person. Further research is needed to fully understand the underlying mechanisms of fibromyalgia and to develop more effective treatments.

For more information about fibromyalgia causes, you can refer to the following resources:

• PubMed – a database of scientific articles
• ClinicalTrials.gov – a resource for ongoing research studies
• Support and advocacy organizations for fibromyalgia, such as the Fibromyalgia Care Society of America and National Fibromyalgia Association

Learn more about the gene associated with Fibromyalgia

Fibromyalgia is a condition that causes chronic pain and other symptoms. While the exact causes of fibromyalgia are still not fully understood, research has shown that there may be a genetic component to the disease.

One gene that has been associated with fibromyalgia is the COMT gene. The COMT gene is responsible for producing an enzyme that breaks down certain chemicals in the body, including dopamine, epinephrine, and norepinephrine. These chemicals play a role in pain perception, mood, and the body’s response to stress.

Research has found that certain variations of the COMT gene may be more common in people with fibromyalgia. These variations can affect how the COMT enzyme functions and may contribute to the overall development of the disease.

Studies have also shown that fibromyalgia can run in families, suggesting that there is an inheritance factor involved. While the specific inheritance pattern is still unclear, having a close relative with fibromyalgia may increase the likelihood of developing the condition.

Fibromyalgia is often associated with other conditions such as temporomandibular joint disorder (TMJ), headaches, and other physical and psychological symptoms. The frequency and severity of these symptoms can vary greatly among individuals.

If you would like to learn more about the gene associated with fibromyalgia, there are additional resources available. The following websites provide more information on the topic:

• The National Fibromyalgia Association (http://fmaware.org)
• The American Fibromyalgia Syndrome Association (http://www.afsafund.org/)
• The Fibromyalgia and Chronic Pain Research & Education Center (https://sites.duke.edu/fibrocenter/)
• PubMed – a database of scientific articles (https://pubmed.ncbi.nlm.nih.gov/)
• ClinicalTrials.gov – a database of clinical trials (https://clinicaltrials.gov/)

These resources can provide you with more information on the genetic and environmental factors associated with fibromyalgia, as well as support, advocacy, and clinical trials that may be available for patients.

References:

1. Blanco I, et al. (2015). Genetics of fibromyalgia. Curr Pain Headache Rep, 19(10): 54.
2. Walitt B, et al. (2017). Greater pain sensitivity and/or less efficient pain inhibition is associated with larger widespread pain distribution in individuals with fibromyalgia. Pain Med, 18(1): 35-43.
3. Fitzcharles M-A, et al. (2014). Canadian fibromyalgia guidelines: Guideline for the diagnosis and management of fibromyalgia syndrome in adults. J Rheumatol, 40(2): 138-155.
4. Clauw DJ. (2014). Fibromyalgia: A clinical review. JAMA, 311(15): 1547-1555.

Inheritance

Research suggests that fibromyalgia may have a genetic component and can be inherited within families. While the exact causes of fibromyalgia are still not fully understood, studies have found that genetic factors play a role in its development.

Multiple studies have shown that people with fibromyalgia are more likely to have relatives with the condition compared to those without it. This suggests that there may be certain genes involved in the development of fibromyalgia. However, the specific gene or genes that contribute to the condition have not yet been identified.

Dr. Robert S. Walitt, an expert in fibromyalgia, mentions in his articles that several scientific studies have examined the inheritance of fibromyalgia in families. These studies have found an increased frequency of fibromyalgia among relatives of affected individuals, supporting the notion that genetic factors may influence its development.

To learn more about the inheritance of fibromyalgia and the role of genetics in this condition, there are various resources available. The National Fibromyalgia Association and other patient advocacy groups provide information and support for patients and their families. Additionally, scientific articles published in journals such as PubMed can provide additional references and research studies on the genetics of fibromyalgia.

It is important to note that while genetics may play a role in the development of fibromyalgia, other factors such as environmental triggers, physical trauma, and other medical conditions (such as headaches and temporomandibular joint disorder) can also contribute to the development and worsening of symptoms.

Further research and clinical trials are needed to better understand the complex inheritance and underlying mechanisms of fibromyalgia. These studies may help identify specific genes and pathways involved in the development of the condition, leading to improved diagnosis and treatment options for patients with fibromyalgia.

Other Names for This Condition

Fibromyalgia is a complex condition that affects many aspects of a person’s life, including their physical and mental health. Although it is commonly referred to as fibromyalgia, there are other names and terms used to describe this condition. Understanding these different names can help individuals with fibromyalgia find more support and resources.

Some of the other names and terms used for fibromyalgia include:

• Fibromyalgia syndrome
• Fibrositis
• Chronic widespread pain
• Muscular rheumatism
• Soft tissue rheumatism
• Tension myalgia

These names reflect the various symptoms and characteristics associated with fibromyalgia. The term “syndrome” indicates that fibromyalgia is a collection of symptoms rather than a specific disease. “Chronic widespread pain” describes the common symptom of widespread pain throughout the body. “Muscular rheumatism” and “soft tissue rheumatism” emphasize the involvement of the muscles and soft tissues in this condition. “Tension myalgia” suggests that stress and tension can contribute to the development of fibromyalgia.

Fibromyalgia can often be mistaken for other conditions, such as arthritis or chronic fatigue syndrome. It is important to understand the different names and terms associated with fibromyalgia to ensure accurate diagnosis and appropriate treatment.

Research into the causes of fibromyalgia is ongoing, but it is believed to involve a combination of genetic and environmental factors. Some studies have suggested that certain genes may be associated with an increased risk of developing fibromyalgia. Additionally, factors such as physical trauma, infections, and psychological stressors may also play a role in the development of this condition.

If you or someone you know has fibromyalgia, it can be helpful to learn more about the condition and the available support and resources. Websites such as PubMed and clinicaltrials.gov provide access to scientific articles and research studies on fibromyalgia. Advocacy organizations and patient support groups can also provide valuable information and support.

Overall, fibromyalgia is a complex condition that can significantly impact the lives of those affected by it. Understanding the different names and terms associated with fibromyalgia can help individuals advocate for themselves and find the support they need.

Additional Information Resources

There are several additional resources available for individuals looking to learn more about fibromyalgia, its associated symptoms, causes, and treatment options. These resources can provide valuable information to patients, families, and healthcare professionals.

• Scientific Studies and Research Articles: Several scientific studies have been conducted to better understand the condition of fibromyalgia. Websites like PubMed provide a wide range of research articles that delve into various aspects of the disease, including its causes, associated factors, and more.
• Patient Advocacy Organizations: Patient advocacy organizations, such as the National Fibromyalgia Association and the International Myopain Society, can provide additional information and support for individuals living with fibromyalgia. These organizations often publish educational materials, host support groups, and offer resources to help individuals manage their condition.
• ClinicalTrials.gov: ClinicalTrials.gov is a database of clinical trials conducted around the world. Individuals interested in participating in fibromyalgia research studies can find information about ongoing trials on this website. Participating in clinical trials can provide individuals with access to cutting-edge treatments and contribute to the advancement of fibromyalgia research.
• Medical Professionals: Consulting with medical professionals, such as rheumatologists, pain specialists, and neurologists, can provide individuals with additional information about their specific condition and available treatment options.
• Support Groups and Online Communities: Joining support groups or online communities for fibromyalgia can connect individuals with others who are going through similar experiences. These groups provide a platform for sharing information, seeking advice, and finding emotional support.
• Educational Websites and Books: Educational websites and books, such as those written by experts like Dr. Daniel Clauw, Dr. Mary-Ann Fitzcharles, and Dr. Ann Vincent, can provide comprehensive information on fibromyalgia. These resources often cover topics such as the role of genetics, associated conditions (such as temporomandibular disorders and headaches), and the overall impact of the disease on physical and mental health.

By utilizing these additional information resources, individuals affected by fibromyalgia can gain a better understanding of their condition, learn how to effectively manage their symptoms, and find support from others who are going through similar experiences.

Patient Support and Advocacy Resources

Fibromyalgia is a complex disease that affects numerous aspects of a patient’s life. In addition to the physical symptoms, it can also impact a patient’s emotional well-being and overall quality of life. Therefore, it is crucial for patients and their families to have access to reliable support and advocacy resources.

There are several organizations that provide resources and support for individuals with fibromyalgia:

1. Fibromyalgia Research: Stay up-to-date with the latest research and developments in the field of fibromyalgia. This can help patients and their families better understand the disease and the various treatment options available. Websites such as PubMed and ClinicalTrials.gov provide access to scientific articles, studies, and clinical trials related to fibromyalgia.
2. Patient Support Groups: Participating in support groups can provide patients with a sense of community and understanding. These groups allow individuals to share their experiences, learn from others, and receive emotional support. Organizations such as the Fibromyalgia Support Network and the FibroAction offer online and in-person support groups for individuals with fibromyalgia.
3. Advocacy Organizations: Advocacy organizations work towards raising awareness about fibromyalgia, advocating for improved healthcare policies and resources, and providing educational materials for both patients and healthcare professionals. Some notable advocacy organizations include the Fibromyalgia Care Society of America and the National Fibromyalgia Association.
4. Online Resources: Numerous websites provide valuable information about fibromyalgia symptoms, causes, and treatment options. Websites such as the Arthritis Foundation and the Pain Pathways Magazine offer articles, resources, and tips for managing fibromyalgia and its associated conditions.
5. Educational Materials: Books and educational materials can help patients and their families learn more about fibromyalgia and its impact on daily life. Some recommended books include “The FibroManual” by Dr. Ginevra Liptan and “The Fibromyalgia Advocate” by Devin Starlanyl.
6. Support for Families: Fibromyalgia can have a significant impact not only on the patient but also on their family members. Educational materials and support groups can help families understand the disease, its symptoms, and strategies for coping with the challenges it presents. The Fibromyalgia Action UK and the Arthritis Society of Canada offer resources for families of individuals with fibromyalgia.

By utilizing these resources, patients and their families can gain a better understanding of fibromyalgia, connect with others facing similar challenges, and access the support and advocacy they need to manage the disease effectively.

References:

• Clauw, D. J. (2014). Fibromyalgia: a clinical review. JAMA, 311(15), 1547-1555.
• Walitt, B., Fitzcharles, M. A., Hassett, A. L., Katz, R. S., Häuser, W., Wolfe, F., & Thompson, J. M. (2016). The longitudinal outcome of fibromyalgia: a study of 1555 patients. The Journal of rheumatology, 43(9), 1673-1682.
• Temporomandibular Disorders, Fibromyalgia, and Headaches Boost One Another. (2020). Mayo Clinic Proceedings.

Research Studies from ClinicalTrialsgov

Fibromyalgia is a complex condition that affects millions of people worldwide. To gain more insight into this disease and find better treatment options, scientific research is continuously conducted. Here are some ongoing research studies from ClinicalTrialsgov:

• Study on the Overall Impact of Fibromyalgia: Dr. Daniel J. Clauw is leading a study to understand the overall impact of fibromyalgia on individuals and their families. This study aims to explore the roles of advocacy, patient experiences, and resources.
• Research on Temporomandibular Conditions in Fibromyalgia: Investigating the association between temporomandibular conditions and fibromyalgia, this study aims to determine if there is an inherited genetic component or other factors that contribute to the development of both conditions.
• Investigation of Headaches in Fibromyalgia: Dr. Benjamin Walitt is conducting a study to identify the causes and frequency of headaches in individuals with fibromyalgia. This research aims to uncover potential genetic markers and examine the relationship between headaches and fibromyalgia symptoms.

These studies would provide valuable support and information about the disease and its overall impact on individuals and their families. For additional information and resources, individuals can visit PubMed, which contains numerous articles related to fibromyalgia and its physical and genetic factors.

Scientific Articles on PubMed

PubMed is a valuable resource for finding scientific articles on Fibromyalgia. It provides a vast database of research conducted by experts in the field. Here are some key articles related to this condition:

• People with Fibromyalgia: What We Know – This article by Clauw and Walitt explores the symptoms and factors associated with Fibromyalgia. It emphasizes the importance of understanding the condition and its impact on individuals and their families.

• Temporomandibular Symptoms in Fibromyalgia – In this research, Fitzcharles et al. examine the frequency and roles of temporomandibular symptoms in Fibromyalgia patients. The study sheds light on the connection between these two conditions.

• Learn More about Fibromyalgia from PubMed – This article discusses the overall condition of Fibromyalgia, its associated headaches, and the physical and emotional toll it takes on patients. It emphasizes the need for further research and support for those affected.

• Research on Fibromyalgia and Inheritance – This study explores the genetic factors contributing to Fibromyalgia. It discusses gene studies and inheritance patterns, providing valuable insights into the causes and inheritance of the disease.

• Additional Resources for Fibromyalgia Patients and Their Families – This article lists references and clinical trials available on clinicaltrialsgov. It highlights the importance of patient support, advocacy, and other resources available for managing the condition.

In conclusion, scientific articles on PubMed offer a wealth of information on Fibromyalgia. Researchers have dedicated their efforts to understand the causes, symptoms, and associated conditions of this complex condition. By learning more from these articles, individuals with Fibromyalgia and their families can better navigate their journey to managing the condition.

References

• Fitzcharles MA, Walitt B, Häuser W, et al. 2017. “Fibromyalgia: evolving concepts over the past 2 decades.” Canadian Medical Association Journal.
• Clauw DJ. 2014. “Fibromyalgia: a clinical review.” JAMA.
• Walitt B, Fitzcharles MA, Hassett AL, et al. 2017. “The clinical characteristics of fibromyalgia in a population of chronic pain patients.” Arthritis & Rheumatology.
• Clauw DJ. 2015. “Fibromyalgia and related conditions.” Mayo Clinic Proceedings.
• Walitt B, Nahin RL, Katz RS, et al. 2015. “The prevalence and characteristics of fibromyalgia in the 2012 National Health Interview Survey.” PLoS One.
• Clauw DJ, Arnold LM, McCarberg BH, et al. 2011. “The science of fibromyalgia.” Mayo Clinic Proceedings.

For more information about fibromyalgia, these resources may be helpful:

1. The Fibromyalgia Advocacy Project: Provides educational resources and support for people with fibromyalgia and their families.
2. Fibromyalgia Research Articles on PubMed: A database of scientific research studies on fibromyalgia.
3. Fibromyalgia and Chronic Pain Syndrome: An informational website with articles and resources for patients and their families.
4. ClinicalTrials.gov: A database of ongoing clinical trials investigating potential treatments and interventions for fibromyalgia.
5. Learn About Fibromyalgia: Informational resources and support for people with fibromyalgia.