The RAD51 gene is an essential genetic component involved in the control of movement. It belongs to the reca motor protein family and is listed in scientific databases such as OMIM and PubMed. Mutations in this gene have been found to be related to various genetic disorders, including congenital conditions and cancer.

In studies and tests conducted on the RAD51 gene, changes and variants have been identified that are associated with breast cancer and other diseases. These findings have provided valuable insights into the genetic basis of these conditions and have highlighted the importance of the RAD51 gene in maintaining genetic health.

References to the RAD51 gene can be found in numerous articles and resources, including the OMIM catalog and PubMed. These references provide additional information on the functions and roles of the RAD51 gene and its proteins.

Health Conditions Related to Genetic Changes

Genetic changes in the RAD51 gene have been associated with various health conditions. The RAD51 gene is essential for DNA repair, especially during cell division and DNA replication. Mutations in this gene can lead to a variety of disorders and diseases.

One of the main health conditions related to genetic changes in the RAD51 gene is cancer. Mutations in RAD51 have been found in breast, ovarian, and other types of cancer. These mutations can affect the function of the RAD51 protein, which is involved in repairing damaged DNA and preventing the growth of cancer cells.

In addition to cancer, genetic changes in the RAD51 gene have also been linked to congenital disorders. These conditions include movement disorders such as mirror movements, where involuntary movements of one side of the body mirror intentional movements on the opposite side.

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To provide more information about the health conditions related to genetic changes in the RAD51 gene, several resources are available for scientific research and testing. The Online Mendelian Inheritance in Man (OMIM) database catalogs information on genes and genetic variants associated with human diseases. The OMIM entry for the RAD51 gene provides additional references to scientific articles and genetic testing resources.

Other databases, such as PubMed, can also be used to find scientific articles on genetic changes in the RAD51 gene and their relation to health conditions. These articles can provide further insights into the functions of the RAD51 gene and its role in various diseases.

Health Conditions Related to Genetic Changes in RAD51 Gene:

• Cancer (breast, ovarian, etc.)
• Congenital movement disorders

Resources for Health Conditions Related to Genetic Changes in RAD51 Gene:

1. Online Mendelian Inheritance in Man (OMIM) database
2. PubMed scientific articles and research
3. Genetic testing resources

Congenital mirror movement disorder

Congenital mirror movement disorder is a genetic condition characterized by involuntary movements on one side of the body that mirror intentional movements on the opposite side. This disorder is caused by a variant in the RAD51 gene, which is essential for genetic information to be properly exchanged between chromosomes during the formation of reproductive cells.

Changes (mutations) in the RAD51 gene can disrupt the normal function of this gene, leading to the development of congenital mirror movement disorder. This condition is often associated with other genetic diseases, such as certain forms of cancer (e.g. breast cancer), due to mutations in other genes involved in the control of cell growth and division.

The RAD51 gene is also related to the motor movements involved in essential biological processes, such as DNA repair and recombination. Scientific research has shown that variants in the RAD51 gene can impact the efficiency of these processes and contribute to the development of various health conditions.

To learn more about congenital mirror movement disorder and related genetic conditions, you can refer to the following resources:

1. OMIM: The Online Mendelian Inheritance in Man (OMIM) database provides detailed information on genetic disorders, including congenital mirror movement disorder. You can find articles, additional references, and genetic testing information on this condition through OMIM.
2. PubMed: PubMed is a scientific database that offers a wide range of research articles on various health conditions, including congenital mirror movement disorder. You can search for specific research studies related to this disorder by using the RAD51 gene and congenital mirror movement disorder as keywords.
3. Human Gene Mutation Database: This database catalogs genetic mutations associated with various diseases, including congenital mirror movement disorder. You can search for specific gene mutations and their impact on this disorder through this resource.
4. Gene Testing Registry: The Gene Testing Registry provides information on genetic testing resources and laboratories that offer tests for various genetic conditions, including congenital mirror movement disorder. You can search for specific genetic tests related to the RAD51 gene through this registry.

In conclusion, congenital mirror movement disorder is a genetic condition caused by a variant in the RAD51 gene. This gene is essential for proper genetic exchange and is also related to other genetic diseases. Resources such as OMIM, PubMed, Human Gene Mutation Database, and the Gene Testing Registry can provide more information about this disorder and related scientific research.

Breast cancer

Breast cancer is a genetic disorder that affects the breast tissue, mainly in women but also in some men. It is one of the most common forms of cancer worldwide, and its incidence has been increasing.

The RAD51 gene, along with other genes and proteins related to DNA repair and genetic movement, is essential for the maintenance of genomic stability. Mutations in the RAD51 gene have been identified in some cases of breast cancer, suggesting its potential role as a genetic factor in the development of the disease.

Genetic testing for mutations in the RAD51 gene can be performed to identify individuals who may have an increased risk of developing breast cancer. This testing can help in the early detection and management of the disease.

There are several resources and registries available for genetic testing and information on breast cancer. The OMIM database, for example, provides a catalog of genetic conditions and genes associated with breast cancer. PubMed is another database that contains scientific articles and references related to the topic.

In addition to genetic testing, there are other tests and screening methods available for the detection and diagnosis of breast cancer. These include mammography, ultrasound, and biopsy procedures. Regular breast self-exams and clinical examinations are also recommended for early detection.

For individuals with a family history of breast cancer or genetic changes associated with the disease, genetic counseling is important. Genetic counseling can provide information on the risks, testing options, and preventive measures available.

It is important to note that not all breast cancer cases are related to genetic mutations. Other factors, such as hormonal changes, lifestyle choices, and environmental exposures, can also contribute to the development of the disease.

In summary, breast cancer is a common and complex disease, with genetic factors playing a role in its development. The RAD51 gene, along with other genes and proteins involved in genetic movement and DNA repair, is essential for maintaining genomic stability. Genetic testing, along with other screening methods and preventive measures, can help in the early detection and management of breast cancer.

Other Names for This Gene

RECA

Breast Cancer 2 Susceptibility Protein 1

HRAD51

RecA Homolog 51

Homologous Recombination Protein Rad51

_HA503E05.2

Oncogene RAD51

RAD51A

RAD51 Homolog A (S. Cerevisiae)

RAD51 Homolog A

RAD51 Homolog A, S. Cerevisiae

BRCC5

Mediator of RAD51 Recombination

Related Movement

Gene Symbol: RAD51

Gene Name: Recombination Repair Protein RAD51 Homolog A

Also Listed As: RAD51 Homolog A, S. Cerevisiae; HRAD51; RAD51 Homolog A; Human RecA Homolog 51; RAD51

Gene Description: Recombination Repair Protein RAD51 Homolog A (Human)

This gene provides instructions for making a protein called RAD51. This protein is essential for DNA repair through a process called homologous recombination, which involves swapping genetic material between two DNA molecules. Homologous recombination is important for repairing damaged DNA, preventing the loss of genetic information, and ensuring the stability of the cell’s genetic material.

In addition to its role in DNA repair, the RAD51 protein is involved in other cellular processes, including meiotic recombination (the process that generates genetic diversity in sperm and egg cells) and regulation of gene expression.

Changes in the RAD51 gene have been associated with a variety of health conditions. Mutations in this gene are directly involved in the development of breast and other cancers. Variants of the RAD51 gene have also been linked to congenital disorders and diseases related to DNA repair.

Scientific articles and resources related to the RAD51 gene can be found in various databases, including PubMed, OMIM (Online Mendelian Inheritance in Man), and the Genetic Testing Registry. These resources provide additional information on the genetic and molecular mechanisms of RAD51, as well as testing and counseling resources for individuals with mutations or variants in this gene.

For more information on RAD51 gene and related movements, visit the following websites:

• PubMed – a database of scientific articles
• OMIM – a catalog of human genes and genetic disorders
• Genetic Testing Registry – a registry of genetic tests and testing laboratories

Additional Information Resources

For additional information on the RAD51 gene, the following resources may be useful:

• Registry and Databases: There are several registries and databases available for accessing information on RAD51 gene mutations and related genetic variants. Some notable ones include:
  • OMIM (Online Mendelian Inheritance in Man): A comprehensive catalog of human genes and genetic disorders. It provides information on the RAD51 gene, including its function, associated diseases, and known mutations.
  • PubMed: A scientific research database that contains articles on various topics, including the RAD51 gene. PubMed can be used to find research articles, scientific papers, and other literature on RAD51 gene mutations, functions, and related topics.
• Movements and Organizations: There are various movements and organizations dedicated to raising awareness about genetic conditions, including those related to the RAD51 gene. These movements often provide support, resources, and information to individuals and families affected by these conditions.
• Testing and Diagnostic Facilities: If you suspect a genetic condition related to the RAD51 gene, it is essential to consult a healthcare professional for appropriate testing and diagnosis. Genetic testing facilities can perform tests to identify specific gene mutations and provide information on related conditions.
• Related Articles and References: Numerous scientific articles and references are available on the RAD51 gene and its significance in various health conditions. These articles provide in-depth knowledge and insights into the function, regulation, and control of the RAD51 gene.

Tests Listed in the Genetic Testing Registry

The Genetic Testing Registry (GTR) is a comprehensive catalog of genetic tests. It features information on the RAD51 gene and its related genes, as well as tests for various genetic conditions and disorders. The GTR is an essential resource for health professionals, scientists, and other individuals seeking information on genetic testing.

The RAD51 gene is an important human gene that is involved in DNA repair. It is essential for maintaining the stability of the genome and preventing the development of genetic mutations. Changes or mutations in the RAD51 gene can lead to various diseases and conditions, including cancer.

In the GTR, there are tests listed for different genetic changes and variants of the RAD51 gene. These tests can provide valuable information about an individual’s genetic makeup and help in the diagnosis and management of certain diseases and conditions.

Many of the tests listed in the GTR are for specific variants or mutations in the RAD51 gene. These tests can detect the presence of these specific genetic changes and provide additional information on their implications for health. The GTR also includes tests for related genes and proteins that are involved in DNA repair and other biological processes.

In addition to information on specific tests, the GTR also provides references to scientific articles, databases, and other resources related to the RAD51 gene and genetic testing. These resources can help researchers and health professionals stay up-to-date with the latest developments in the field.

The GTR is a mirror of the Genetic Testing Registry (GTR), which is a freely accessible online database of genetic test information. The GTR contains information on the availability, purpose, and limitations of genetic tests, as well as their clinical validity and utility.

In conclusion, the Genetic Testing Registry (GTR) provides a comprehensive catalog of genetic tests, including tests for the RAD51 gene and related genes. It is an essential resource for health professionals, scientists, and individuals seeking information on genetic testing for various diseases and conditions.

Scientific Articles on PubMed

PubMed is a database that contains a vast collection of scientific articles on various topics. Below are some resources on the RAD51 gene and related topics:

• Cancer and RAD51 gene: Several articles on PubMed discuss the role of the RAD51 gene in cancer development. These articles explore the genetic changes, mutations, and variants of the RAD51 gene that may be associated with different types of cancer, such as breast cancer.
• RECA gene and RAD51 gene: The RECA gene is closely related to the RAD51 gene. PubMed provides valuable information on how these genes function together and their importance in DNA repair processes.
• Genetic Disorders and RAD51 gene: PubMed lists numerous diseases and genetic disorders associated with mutations in the RAD51 gene. These diseases range from relatively common conditions to rare congenital disorders affecting motor control and movements.
• OMIM and RAD51 gene: The Online Mendelian Inheritance in Man (OMIM) is a comprehensive catalog of genetic disorders. PubMed references several articles that link specific disorders to the RAD51 gene, making it a useful resource for genetic testing and additional information.
• Other genes related to RAD51: In addition to the RAD51 gene, PubMed contains articles on other genes that are essential for DNA repair processes and are linked to various diseases. These genes include proteins such as RAD52 and RAD54.

These articles and more can be found on PubMed, providing researchers and healthcare professionals with valuable scientific information on the RAD51 gene and its role in various diseases.

Catalog of Genes and Diseases from OMIM

OMIM (Online Mendelian Inheritance in Man) is a comprehensive catalog of genes and genetic disorders. It provides detailed information on various genes and their associated diseases, making it a valuable resource for researchers, healthcare professionals, and individuals seeking information regarding genetic conditions.

The OMIM database contains a vast amount of data on different genes and diseases, including information on their clinical features, inheritance patterns, mutations, and related scientific articles. It serves as a mirror to the ongoing scientific research and discoveries in the field of genetics.

The genes listed in the OMIM catalog are classified based on their biological functions and their involvement in various diseases. These genes play an essential role in maintaining human health and are crucial for normal physiological processes.

One of the genes included in the OMIM database is RAD51. RAD51 is a motor protein involved in DNA repair and recombination. Mutations in the RAD51 gene can lead to various genetic disorders, including breast cancer and congenital movement disorders.

For each gene and disease listed in the OMIM catalog, additional resources and references are provided. These resources include links to other genetic databases, scientific articles from PubMed, and control databases for variant changes.

The OMIM catalog serves as a vital tool for genetic testing and diagnosis. It enables healthcare professionals to identify and understand the genetic basis of various diseases, providing valuable insights into their underlying causes and potential treatment options.

In conclusion, the OMIM catalog of genes and diseases provides a comprehensive resource for understanding the genetic basis of various conditions. It offers detailed information on genes, associated diseases, mutations, and references to scientific articles. With its wide range of information and resources, OMIM plays a crucial role in advancing our understanding of genetic disorders and improving healthcare outcomes.

Gene and Variant Databases

Gene and variant databases are essential resources for genetic research and testing. They provide a wealth of information on different genes, variants, and associated disorders. Scientists rely on these databases to understand the genetic basis of diseases, to identify mutations and changes in specific genes, and to find references for further scientific articles.

One of the most widely used databases is the Online Mendelian Inheritance in Man (OMIM). It catalogs various genetic disorders and conditions, providing information on their clinical features, inheritance patterns, and related genes. OMIM also lists the genetic changes and mutations associated with each disorder or condition.

The Human Gene Mutation Database (HGMD) is another valuable resource. It contains information on mutations in human genes linked to various diseases, including congenital disorders, cancer, and motor movement conditions. The HGMD provides information on the genetic changes, protein effects, and references to scientific articles.

The RECA database focuses specifically on the RAD51 gene, which plays a crucial role in genetic recombination and DNA repair. It lists genetic changes and variants in the RAD51 gene, providing information on their effects on protein function and their association with cancer, particularly breast cancer.

Other databases, such as the Leiden Open Variation Database (LOVD) and the Human Gene Mutation Database (HGMD), provide comprehensive information on genetic variants and their associations with diseases. These databases include information on variant nomenclature, clinical significance, population frequencies, and sources of evidence.

When conducting genetic testing, researchers and clinicians often refer to these databases to interpret the significance of genetic variants detected in patients. Having access to these databases allows them to compare their findings to known variants and determine their clinical relevance.

Overall, gene and variant databases are invaluable resources for researchers and clinicians working in the field of genetics. They provide access to a wealth of information on specific genes, genetic changes, associated disorders, and scientific references. These databases play a critical role in advancing our understanding of genetic diseases and guiding genetic testing.

References

• Reca, B., → Recombinase A protein
• OMIM → Online Mendelian Inheritance in Man
• PubMed → A database of scientific articles
• Genetic Testing Registry → Information on genetic tests
• OMIM → Catalog of human genes and genetic disorders
• Breast Cancer Information → Information on breast cancer

Additional information on the RAD51 gene and related genetic movements and changes can be found at the following resources:

• OMIM – https://omim.org/
• PubMed – https://pubmed.ncbi.nlm.nih.gov/
• Genetic Testing Registry – https://www.ncbi.nlm.nih.gov/gtr/
• Reca Catalog – https://www.reca-recombinase.nl/reca/

These resources provide a wealth of information on the RAD51 gene, its variants, and their role in various genetic disorders and conditions. They also offer testing options, as well as control and registry for movement-related disorders and other essential genetic changes.