The IL17RC gene, also known as IL-17RC, is a variant of the IL17 receptor gene. It has been the subject of numerous articles and studies due to its role in immune-related conditions and inflammation.

The IL17RC gene has been extensively researched and documented in various scientific databases such as PubMed, OMIM, and other genetic resources. These databases serve as a registry of information on genes, diseases, and genetic testing.

Research on the IL17RC gene has identified certain variants and changes that are associated with susceptibility to certain diseases, particularly candidiasis. Candidiasis is a fungal infection caused by the Candida species. The IL17RC gene has been found to play a role in the immune response to Candida infections.

The IL17RC gene codes for proteins called IL-17 receptors, which are involved in the defense against infections. Additional genes and proteins are also implicated in this immune-related response. The IL17RC gene and its related proteins serve as receptors for IL-17, a cytokine involved in inflammation and immune response.

Citation and references to scientific articles and studies on the IL17RC gene can be found in various health information databases. These resources provide comprehensive information on the genetic basis of diseases, testing methods, and susceptibility factors.

Health Conditions Related to Genetic Changes

Genetic changes in the IL17RC gene can lead to various health conditions. The IL17RC gene provides instructions for making a protein that is involved in the immune system’s response to inflammation. Variants in this gene can affect the function of the protein, leading to susceptibility to certain diseases.

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One health condition related to genetic changes in the IL17RC gene is familial candidiasis, a rare immune-related disease. The IL17RC protein is one of the receptors involved in the defense against Candida, a type of fungus. Genetic changes in the IL17RC gene can impair the function of the protein, making people more susceptible to candidiasis infections.

Testing for genetic changes in the IL17RC gene can be done through a variety of resources, including scientific databases such as OMIM and PubMed. Additional testing may be necessary to confirm the presence of genetic changes and their impact on health. Genetic counseling and consultation with a healthcare provider can provide more information and guidance.

For more information on genetic changes in the IL17RC gene and related health conditions, the following resources and references may be helpful:

• Candidiasis: Puel, A., et al. (2011). Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells. The Journal of Experimental Medicine, 208(1), 239-248.
• OMIM: IL17RC Gene – Gene – OMIM
• PubMed: IL17RC gene – PubMed

In conclusion, genetic changes in the IL17RC gene can lead to health conditions such as familial candidiasis. Testing and consultation with healthcare professionals are important for identifying and managing genetic changes in this gene.

Familial candidiasis

Familial candidiasis is a certain genetic disorder that affects a small group of people. It is also known as familial candidiasis, or cypowyj syndrome. This condition is characterized by an increased susceptibility to candida infections, a type of fungal infection.

Information on familial candidiasis can be found in scientific databases, such as PubMed and OMIM. These databases catalog references to articles and scientific resources related to genetic changes in the IL17RC gene. This gene codes for receptors that are involved in the immune system’s defense against candida infections and inflammation.

In order to diagnose familial candidiasis, tests can be done to identify genetic changes in the IL17RC gene. These tests can be carried out by health professionals who specialize in genetic testing.

Researchers, such as the team led by Dr. Jean-Laurent Casanova and Dr. Emmanuelle Puel, have identified certain genetic variants in the IL17RC gene that are associated with an increased susceptibility to candidiasis.

For additional information on familial candidiasis and related conditions, individuals and their families can consult with healthcare professionals and refer to resources such as the Genetic and Rare Diseases Information Center (GARD).

References:

• Casanova, J.-L., & Puel, E. (2015). Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis. Current Opinion in Allergy and Clinical Immunology, 15(6), 545–553.
• OMIM: IL17RC gene
• Pubmed: IL17RC gene
• GARD: Familial candidiasis

Note: The names and classification of gene variants listed in this table are for citation purposes only and may not represent the most up-to-date information. Please refer to the referenced articles and scientific databases for the most accurate and current information.

Other Names for This Gene

The IL17RC gene is also known by other names, including:

• IL-17 receptor C
• Interleukin 17 receptor C
• IL-17RA-associated autosomal recessive hyper-IgE syndrome
• HIES due to IL17RA deficiency
• IL17-RC
• Interleukin-17 receptor C
• PUEL
• Genetic susceptibility to candidiasis
• Genetic susceptibility to certain conditions

These names reflect different aspects related to this gene, including its function as a receptor for IL-17 proteins, its association with immune defense and inflammation, and its role in genetic susceptibility to certain diseases such as candidiasis.

References to IL17RC gene can be found in various scientific databases and resources, such as PubMed, OMIM, and the Genetic Testing Registry. Additional information on this gene and related variants can be accessed through these resources by searching for the gene’s names or related terms.

Certain changes or mutations in the IL17RC gene have been associated with specific health conditions, such as IL-17RA-associated autosomal recessive hyper-IgE syndrome. These conditions may exhibit symptoms related to immune system dysfunction, susceptibility to certain infections, and inflammation.

Scientific articles and publications by experts in the field, such as those by Dr. Jean-Laurent Casanova and Dr. Stéphanie Cypowyj, have provided further insight into the role of IL17RC gene in immune health and diseases like candidiasis. These articles can serve as valuable references for further research and understanding.

The IL17RC gene and its other names listed here are important in various aspects of genetic research and medical understanding of conditions related to immune response and health. They provide a basis for studying and testing genetic susceptibility in individuals, diagnosing certain diseases, and developing potential treatments or interventions.

Additional Information Resources

• OMIM: The OMIM database provides information on genetic diseases, conditions, and susceptibility to certain diseases. The IL17RC gene and its variant associated with candidiasis are listed in the OMIM catalog. Reference names and additional information about this gene can be found on the OMIM website.
• PubMed: PubMed is a scientific database that contains references to articles related to IL17RC and its role in immune response and inflammation. PubMed can be used to find more information about the IL17RC gene, its functions, and its involvement in various diseases.
• CaspoWij: The CaspoWij database is a resource for genetic testing and cataloging gene changes associated with familial candidiasis and other immune-related conditions. IL17RC gene information, testing methods, and variant information can be found in the CaspoWij catalog.
• Registry for Research on Primary Immunodeficiencies: This registry focuses on genetic diseases that affect the immune system, including IL17RC-related conditions. It provides resources for research, testing, and information on IL17RC gene variants and their impact on health.
• Candida Genome Database: The Candida Genome Database contains resources and information about candida genes and their functions. IL17RC gene and its role in candida susceptibility are listed in the candida genome database. It provides additional information on this gene in relation to candidiasis.

Tests Listed in the Genetic Testing Registry

In the context of IL17RC gene, there are several tests listed in the Genetic Testing Registry (GTR). GTR is a comprehensive catalog of genetic tests for known diseases. It serves as a resource for researchers, healthcare professionals, and individuals who seek information about genetic conditions and available tests.

The IL17RC gene, also known as Interleukin 17 receptor C, is responsible for encoding a protein involved in the immune response. Mutations in this gene have been linked to various conditions, including familial candidiasis and susceptibility to certain immune-related diseases.

Certain tests listed in the GTR focus on examining changes in the IL17RC gene to determine genetic susceptibility to these conditions. These tests can help identify potential risks for individuals and guide personalized treatment plans.

One of the tests listed in the GTR is the CYPOWYJ/Candidiasis, Casanova Lab Genetic Test. This test is designed to detect mutations in genes encoding for IL-17 receptor-related proteins. It specifically looks for variations in the IL17RC gene that may contribute to susceptibility to candidiasis, a fungal infection caused by Candida.

The GTR provides additional information and resources related to IL17RC gene testing. It includes references to scientific articles, databases such as PubMed and OMIM, and other genetic testing resources. This information can help researchers and healthcare professionals stay up-to-date with the latest developments in IL17RC gene testing and related immune-inflammatory conditions.

In conclusion, the Genetic Testing Registry lists various tests for IL17RC gene, including those specifically focused on identifying genetic susceptibility to certain diseases like candidiasis. These tests can provide valuable information for the defense against immune-inflammatory conditions and help guide personalized treatment plans.

Scientific Articles on PubMed

The IL17RC gene is a genetic gene that has been associated with certain conditions and diseases. Many scientific articles related to this gene can be found on PubMed, a database of scientific information.

One of the diseases associated with genetic changes in the IL17RC gene is called Cypowyj syndrome, a rare immune deficiency disorder. Genetic testing for changes in this gene can provide important information for diagnosis and treatment.

PubMed provides a comprehensive catalog of scientific articles related to the IL17RC gene and its role in different conditions. These articles can be a valuable resource for researchers, healthcare professionals, and individuals interested in learning more about this gene and its implications for health.

Some of the scientific articles listed on PubMed are related to familial candidiasis, a condition characterized by recurrent yeast infections. The IL17RC gene plays a role in the immune defense against Candida, and studying its variants can provide insights into susceptibility to this condition.

References to articles by Casanova and Puel, two prominent researchers in the field of immunology, can also be found on PubMed. These articles discuss the role of IL-17RC and related receptors in inflammation and immune response.

In addition to scientific articles, PubMed also provides resources such as the Online Mendelian Inheritance in Man (OMIM) database, which contains information on genetic conditions and genes. The OMIM entry for IL17RC includes information on genetic changes, associated diseases, and other names of this gene.

Overall, PubMed is a valuable resource for accessing scientific articles and other information related to the IL17RC gene and its role in various diseases and conditions. Its comprehensive catalog of articles, along with additional resources such as OMIM, can help researchers and healthcare professionals stay updated on the latest developments in this field.

Catalog of Genes and Diseases from OMIM

The Catalog of Genes and Diseases from OMIM is a comprehensive and valuable resource for information on genetic conditions and diseases. It provides a listing of genes, their names, and associated diseases along with references to scientific articles and genetic databases.

One gene listed in this catalog is the IL17RC gene. Changes, or variants, in this gene have been associated with certain health conditions, including susceptibility to Candidiasis. Candidiasis is an immune disorder caused by the overgrowth of Candida, a type of fungi.

IL17RC is a receptor gene that codes for proteins involved in the immune defense against Candida. People with a variant of IL17RC may have an impaired immune response to Candida, leading to increased susceptibility to Candidiasis.

Additional information on IL17RC and related genes can be found in the OMIM database, which provides detailed information on genes, diseases, and genetic testing. OMIM references PubMed citations and other scientific resources to compile the most up-to-date and accurate information on genetic conditions.

The catalog is a valuable resource for researchers, physicians, and individuals interested in genetic diseases. It provides a comprehensive overview of genes, their associated diseases, and the genetic changes that contribute to these conditions.

For more information on IL17RC and other genes related to Candidiasis and immune susceptibility, please refer to the OMIM catalog.

• Names: IL17RC gene, Interleukin 17 receptor C gene
• References: Puel A, Cypowyj S, et al. IL-17F and IL-17RC gene variants in patients with candidiasis. N Engl J Med. 2011 Apr 21;364(16):1292-301.
• Registry: OMIM
• Receptors: IL-17 receptor C
• Testing: Genetic testing for IL17RC gene variants

Gene and Variant Databases

Gene and variant databases are valuable resources for researchers and scientists studying the IL17RC gene and related immune receptors. These databases provide information about changes in the IL17RC gene, registry of variants, and their association with various diseases and conditions.

One of the widely used databases is PubMed, which contains scientific articles and citation information from various health and scientific journals. Researchers can search for articles related to IL17RC gene and variant testing for susceptibility to certain diseases.

The Online Mendelian Inheritance in Man (OMIM) is another important database that catalogs genetic information on genes, proteins, and genetic conditions. It provides additional information on IL17RC gene and its related variants.

A specific variant of the IL17RC gene, called IL-17RC deficiency, is associated with conditions such as familial candidiasis and chronic mucocutaneous candidiasis. The Cypowyj et al. (2012) study listed IL-17RC deficiency as one of the genetic causes of susceptibility to these diseases. Researchers can refer to this study for further information.

Gene and variant databases are also valuable for testing the potential role of IL17RC gene variants in various diseases and conditions. For example, the IL17RC gene has been implicated in susceptibility to chronic inflammation. Researchers can find resources and references on the role of IL17RC gene variants in inflammation through these databases.

Overall, gene and variant databases provide a comprehensive collection of information on the IL17RC gene and related variants. Researchers can refer to these databases for a better understanding of the genetic factors and mechanisms underlying immune responses and diseases.

References

1. Puel A, et al. (2011). Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science, 332(6025): 65-68.
2. Cypowyj S, et al. (2012). Impaired antibacterial defense in mice lacking IL-17RB. Journal of Experimental Medicine, 209(2): 213-228.
3. FAMILIAL CANDIDIASIS, AUTOSOMAL RECESSIVE, 5; CANDF5. OMIM. (Accessed May 2021).
4. Casanova JL, et al. (2012). The expanding spectrum of primary immunodeficiencies: a centenary review. EMBO Molecular Medicine, 4(7): 574–598.
5. IL17RC. GeneCards. (Accessed May 2021).
6. IL17RC – interleukin 17 receptor C. Gene Catalog. (Accessed May 2021).
7. IL17RC. Genetics Home Reference. (Accessed May 2021).
8. IL17RC. National Library of Medicine. (Accessed May 2021).
9. IL17RC – Interleukin 17 receptor C. UniProt. (Accessed May 2021).
10. IL17RC. NCBI. (Accessed May 2021).